Abstract
Adult respiratory distress syndrome (ARDS), defined by Ashbaugh et al. [1] as an acute arterial hypoxia, has a high mortality. In the NIH study [8] in the early 1970s mortality was 80%–90%, and in the most recent European study by Artigas [3], for patients in Morel’s stages III–IV [7], the percentage is 70%. In this study we discuss ARDS patients in stages III and IV. Death, however, is not only caused by ARDS but also by the basic disease. The lungs of patients with severe progressive ARDS, i.e., with ARDS developing continuously for days or even weeks, show disturbances of ventilation and perfusion that are not only regionally distributed. They range from ventilated nonperfused to perfused nonventilated alveolar regions without fixed boundaries.
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References
Ashbaugh DG, Bigelow DB, Petty TL, Levine BE (1967) Acute respiratory distress in adults. Lancet 11:319–333
Brandt L, Mertzlufft FO, Rudolf B, Dick W (1988) In-vivo-Nachweis des Christiansen-Douglas-Haldane-Effektes unter klinischen Bedingungen. Anaesthesist 37:529–534
European ARDS Collaborative Working Group (1988) Adult respiratory distress syndrome (ARDS). Clinical predictors, pronostic factors and outcome. Intensive Care Med 14 [Suppl 1]:300
Gattinoni L, Agostoni A, Pesenti A, Pelizzola A, Rossi G, Langer M, Vesconti S, Uziel L, Fox U, Longoni F, Kolobow T (1980) Treatment of acute respiratory failure with low frequency positive-pressure ventilation and extracorporeal removal of CO2. Lancet 11:29
Jardin F (1979) Pulmonary hemodynamics and gas exchange during venoarterial bypass with membrane-lung oxygenation. In: Unger, Regnier B, Gastine H, Lemaire F (eds) Assisted circulation. Springer, Berlin Heidelberg New York
Kolobow T, Gattinoni L, Tomlinson TA, Pierce JE (1977) Laboratory report. Control of breathing using an extracorporeal membrane lung. Anaesthesiology 46:138–141
Morel DR, Dargent F, Bachmann M, Suter PM, Junod AF (1985) Pulmonary extraction of serotonin and propranolol in patients with adult respiratory distress syndrome. Am Rev Respir Dis 132:479
National Heart Lung and Blood Institute. Division of Lung Diseases (1970) Extracorporeal support for respiratory insufficiency: a collaborative study. Nahonal Institute of Health, Bethesda
Zapol WM, Snider MT, Hill JD (1979) Extracorporeal membrane oxygenation in severe acute respiratory failure. JAMA 242:2193
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© 1989 Springer-Verlag Berlin Heidelberg
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Lennartz, H. (1989). Principles and Present Role of Extracorporal Elimination of CO2 in the Therapy of Respiratory Failure. In: Reinhart, K., Eyrich, K. (eds) Clinical Aspects of O2 Transport and Tissue Oxygenation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83872-9_22
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DOI: https://doi.org/10.1007/978-3-642-83872-9_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-51470-1
Online ISBN: 978-3-642-83872-9
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