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Intensivtherapie des Myokardinfarktes — Limitierung der Infarktgröße

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Verhandlungen der Deutschen Gesellschaft für Innere Medizin

Zusammenfassung

Der akute Myokardinfarkt gehört mit der instabilen Angina pectoris und dem plötzlichen Herztod zu den drei akuten Koronarsyndromen, die sich nur im Ausmaß und der Geschwindigkeit der Thrombusentstehung unterscheiden [16]. Ein solcher Koronarverschluß (Abb. 1) führt zu einem akuten Ausfall der Myokardperfusion und innerhalb weniger Sekunden zum Ausfall der Funktion des nicht mehr perfundierten Myokards. Wird das Gefäß innerhalb weniger Minuten wieder geöffnet [34, 37, 38, 48], erholt sich das Myokard vollständig. Bleibt die Durchblutung längere Zeit blockiert, entwickelt sich ein Infarkt, der von subendokardial nach epikardial sich ausbreitet [24, 46, 47, 52, 53]. t bedeutet eine kurze Ischämie mit Ausbildung einer Innenschichtischämie oder, wie man heute sagt, eines Non-Q-Infarktes, eine längere Ischämiezeit eine transmurale Infarzierung mit Ausbildung eines sog. Q-Wellen-Infarktes.

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Erbel, R. et al. (1989). Intensivtherapie des Myokardinfarktes — Limitierung der Infarktgröße. In: Miehlke, K. (eds) Verhandlungen der Deutschen Gesellschaft für Innere Medizin. Verhandlungen der Deutschen Gesellschaft für Innere Medizin, vol 95. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83864-4_35

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