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Heart Size Reduction in Acromegalic Patientes Treated with the Long-Acting Somatostatin-Analogue SMS 201–995 (Somatostatin®)

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Endocrinology of the Heart

Abstract

Cardiomegaly by hypertrophy of the heart in acromegalic patients — prevalence 85% in our patients with acromegaly [1] — is often complicated by complex arrhythmias and gradual cardiac-insufficiency [1, 3, 8]. The aim of the study was to evaluate the extend of heart size reduction in acromegalic patients under longterm-treatment with the long-acting somatostatin-analgoue SMS 201–995 (Sandostatin®, Sandoz) [2, 5, 7]. All patients had been treated before SMS 201–995 therapy by neurosurgery and/or radiation and medical treatment with bromocriptine (Pravidel®), so that hypersomatotropism before SMS 201–995 therapy was only moderate (s. Table la).

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References

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© 1989 Springer-Verlag Berlin Heidelberg

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Althoff, PH., Schmidt, K., Rübesam, D., Harris, A.G., Jungmann, E., Schöffling, K. (1989). Heart Size Reduction in Acromegalic Patientes Treated with the Long-Acting Somatostatin-Analogue SMS 201–995 (Somatostatin®). In: Kaufmann, W., Wambach, G. (eds) Endocrinology of the Heart. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83858-3_56

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  • DOI: https://doi.org/10.1007/978-3-642-83858-3_56

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51409-1

  • Online ISBN: 978-3-642-83858-3

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