Artrial Natriuretic Peptide Concentrations in Preeclampsia
During pregnancy various humoral and functional mechanisms were recognized, that regulate the water and electrolyte household. In preeclampsia, increased water-sodium retention results from a variety of pathophysiological changes in the endocrinological system. There are also organ-specific changes, such as renal clearance reduction up to 30% in comparison to normal pregnancy. For many years, physiologists expected to find additional cardial mechanisms that influence homeostasis. In 1981, de Bold  identified ANP a new humoral factor that leads to increased water and sodium excretion. The influence of ANP in preeclampsia has been the subject of controversial discussion.
Key wordsPregnancy induced hypertension Preeclampsia
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