Skip to main content

Artrial Natriuretic Peptide Concentrations in Preeclampsia

  • Conference paper
Endocrinology of the Heart
  • 83 Accesses

Abstract

During pregnancy various humoral and functional mechanisms were recognized, that regulate the water and electrolyte household. In preeclampsia, increased water-sodium retention results from a variety of pathophysiological changes in the endocrinological system. There are also organ-specific changes, such as renal clearance reduction up to 30% in comparison to normal pregnancy. For many years, physiologists expected to find additional cardial mechanisms that influence homeostasis. In 1981, de Bold [3] identified ANP a new humoral factor that leads to increased water and sodium excretion. The influence of ANP in preeclampsia has been the subject of controversial discussion.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Cowan BD, Martin JN, Tucker JM, Martin RW, Morrison JC, Kikokawa T, Mukhergèe AB (1988) High plasma concentrations of human atrial natriuretic polypeptide in women with pregnancy — induced hypertension. Proceedings ISSHP, Montreal, p 45

    Google Scholar 

  2. Cusson JR, Gutkowska J, Rey E, Mickon N, Boucher M, Larochelle P (1985) Plasma concentration of atrial natriuretic factor in normal pregnancy. N Engl J Med 313: 1230–1231

    PubMed  CAS  Google Scholar 

  3. De Bold AJ, Borenstein HB, Veress AT, Sonnenberg H (1981) A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci 28: 89–94

    Article  PubMed  Google Scholar 

  4. Eastmann J, Bell ST, Dieckmann WJ (1952) Definition and classification of toxaemias brought up to date. American Committee on Maternal Welfare, Chicago

    Google Scholar 

  5. Niesert S, Gunter HH, Kaulhausen H (1987) Atrial natriuretic peptidide during pregnancy. Lancet 11: 404–405

    Article  Google Scholar 

  6. Rutherford AJ, Anderson JV, Elder MG, Bloom SR (1987) Release of atrial natriuretic peptide during pregnancy and immediate puerperium. Lancet 1: 928–929

    Article  PubMed  CAS  Google Scholar 

  7. Steegers EA, Tan AC, Coumans HJ, Benraad TJ, Groeneveld EA, Jongsma HW, Hein PR (1988) Atrial natriureticpeptide, aldosterone, plasma renin activity and diuresis in puerperium. Proceedings JSSHP, Montreal, p 46

    Google Scholar 

  8. Thomsen JK, Storen TL, Thambsborg G, De Nully M, Bodker B, Skouby S (1987) Atrialnatriuretic peptide concentrations in preeclampsia. Br Med J 294: 1508–1510

    Article  CAS  Google Scholar 

  9. Weidmann P, Hasler L, Gnädinger MP, Lang RE, Uehlinger DE, Shaw S, Rascher W, Renbi FC (1986) Blood levels and renal effects of atrial natriuretic peptide in normal man. J Clin Invest 77: 734–742

    Article  PubMed  CAS  Google Scholar 

  10. Weil J, Bidlingmaier F, Döhlemann C, Kühnle V, Strom T, Lang RE (1986) Comparison of plasma atrial natriuretic peptide levels in healthy children from birth to adolescence and in children with cardiac diseases. Pediatr Res 20: 1328–1331

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Casper, F., Seufert, R., Lang, R.E. (1989). Artrial Natriuretic Peptide Concentrations in Preeclampsia. In: Kaufmann, W., Wambach, G. (eds) Endocrinology of the Heart. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83858-3_45

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83858-3_45

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51409-1

  • Online ISBN: 978-3-642-83858-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics