Artrial Natriuretic Peptide Concentrations in Preeclampsia

  • F. Casper
  • R. Seufert
  • R. E. Lang
Conference paper


During pregnancy various humoral and functional mechanisms were recognized, that regulate the water and electrolyte household. In preeclampsia, increased water-sodium retention results from a variety of pathophysiological changes in the endocrinological system. There are also organ-specific changes, such as renal clearance reduction up to 30% in comparison to normal pregnancy. For many years, physiologists expected to find additional cardial mechanisms that influence homeostasis. In 1981, de Bold [3] identified ANP a new humoral factor that leads to increased water and sodium excretion. The influence of ANP in preeclampsia has been the subject of controversial discussion.

Key words

Pregnancy induced hypertension Preeclampsia 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • F. Casper
    • 1
  • R. Seufert
    • 1
  • R. E. Lang
    • 2
  1. 1.Department of Obstetrics and GynecologyUniversity of MainzGermany
  2. 2.German Institute for High Blood Pressure ResearchUniversity of HeidelbergGermany

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