Right Atrial Inversion Causes Increased ANF Secretion During Cardiopulmonary Bypass

  • M. Dahm
  • S. Nikolic
  • K. Owusu
  • D. Heublein
  • E. L. Yellin
  • J. BurnettJr.
  • R. W. M. Frater
Conference paper

Abstract

ANF is a polypeptide with important influence on blood pressure, cardiac output and sodium excretion. As the physiological stimulus for ANF release right atrial volume, i.e. right atrial distension has been demonstrated in animals [3, 4] and patients [5, 7]. Significant changes in ANF serum level have been reported during CPB [2]: after onset of CPB ANF level rises and stays elevated. During CPB RAP is very low or negative so that right atrial distension cannot account for this increase in secretion. Aim of this study was to determine if the inversion of the right atrium during CPB causes the increased release of ANF.

Key words

ANF Cardiopulmonary Results bypass Atrial inversion 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • M. Dahm
    • 1
    • 2
  • S. Nikolic
    • 1
    • 2
  • K. Owusu
    • 1
    • 2
  • D. Heublein
    • 1
    • 2
  • E. L. Yellin
    • 1
    • 2
  • J. BurnettJr.
    • 1
    • 2
  • R. W. M. Frater
    • 1
    • 2
  1. 1.Department of Cardiothoracic SurgeryAlbert Einstein College of MedicineBronxUSA
  2. 2.Mayo ClinicRochesterUSA

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