Localization of Hormones by Antibodies
Hormones are substances produced by endocrine cells which are carried by the blood from the site of their secretion to the receptors of their target cells. At present hormones, including paracrine and autocrine substances, and neural messengers form the group of regulatory substances. Chemically they are peptides, proteins, glycoproteins, steroid hormones, iodothyronines or biogenic amines. Antibodies can be raised against many, if not all hormones, but the immunogenicity of the different substances varies widely.
KeywordsEndocrine Cell Colloidal Gold Original Magnification Electron Microscopical Level Pancreatic Endocrine Tumor
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- Falkmer S, Hakanson R, Sundler F (eds) (1984) Evolution and tumour pathology of the neuroendocrine system. Elsevier, AmsterdamGoogle Scholar
- Heitz PU (1987) Neuroendocrine tumor markers. In: Seifert G (ed) Morphological tumor markers. General aspects and diagnostic relevance. Springer, Berlin Heidelberg New York, pp 279–306 (Current topics in pathology vol 77 )Google Scholar
- Heitz PU, Steiner H, Halter F, Egli F, Kapp JP (1971) Multihormonal amyloid-producing tumour of the islets of Langerhans in a twelve year old boy. Virchows Arch [A] 353: 312–324Google Scholar
- Ryffde Lèche A, Staub JJ, Kohler-Faden R, Müller-Brand J, Heitz PU (1986) Thyroglobulin production by malignant thyroid tumors: an immunocytochemical and radioimmunoassay study. Cancer 57: 1045–1053Google Scholar
- Sternberger LA (1986) Immunocytochemistry, 3rd edn. Wiley, New YorkGoogle Scholar