Abstract
Chromaffin tumors are defined as neoplasias composed of catecholamine-producing, -storing, and -secreting cells. They therefore develop not only in the adrenal medulla but also in sympathetic paraganglia. Regardless of their intra- or extra-adrenal localization, we shall use the term pheochromocytoma for all expansive growing forms of these tumors and the term pheochromoblastoma for all infiltrating and metastasizing forms (Table 1; Käser 1985). However, it must be emphasized that even the nonmalignant pheochromocytoma must be considered as lifethreatening disease. In fact, its endocrine activity may lead to death if the tumor remains unrecognized and untreated. However, if correctly diagnosed, this neural crest tumor can be removed by surgery, and most patients can thus be cured.
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References
Beierwaltes WH (1985) A new method of identifying pheochromocytoma and proving that a “mass” is a “Pheo”. J Urol 134: 105
Beutter D, Chatal JF, Brunet G, Charbonnel B (1987) Treatment of malignant pheochromocytoma with I-131 metaiodobenzylguanidine. Ann Endocrinol 48: 53–57
Bouvier JF, Maiassi N, Fleury MC, Mornex R, Lahneche BE (1987) Diagnosis and treatment of metastatic pheochromocytomas by I-131 MIBG. Tumour Biol 8: 362–363
Bravo EL, Tarazi RC, Gifford RW, Steward BH (1979) Circulating and urinary catecholamines in pheochromocytoma. N Engl. J. Med. 301: 682–686
Chatal JF, Charbonnel B (1985) Comparison of jodobenzylguanidine imaging with computed tomography in locating pheochromocytoma. J. Clin. Endocrinol Metab 61: 769–772
Cordes U (1985) Nebennierenmark. In: Kümmerle F, Lenner V (eds) Erkrankungen der Nebennieren. Thieme, Stuttgart, pp 96–120
Coupland RE (1965) The natural history of the chromaffin cell. Longmans, Green, London
Coupland RE (1981) Catecholamine secreting tissues. In: Fotherby K, Pal SB (eds) Hormones in normal and abnormal human tissues, De Gruyter, Berlin, pp 589–633
Fink IJ, Reining JW, Dwyer AJ, Doppman JL, Marston-Linehan W, Keiser HR (1985) MR—imaging of pheochromocytomas. J. Comput Assist Tomogr. 9: 454–458
Fischer M, Galanski M, Winterberg B, Vetter H (1985) Localization procedures in pheochromocytoma and neuroblastoma. Cardiology 72 (Suppl 1): 143–146
Fries JG, Chambertin JA (1968) Extra-adrenal pheochromocytoma: literature review and report of a cervical pheochromocytoma. Surgery 63: 268–279
Gauer J.-M, Käser H, Zingg EJ (1988) Klinik, Diagnose und Therapie des Phäochromozytoms. Aktuel Urol 19: 7–12
Gifford RW, Bravo EL, Manger WM (1985) Diagnosis and management of pheochromocytoma. Cardiology 72 (Suppl 1): 126–130
Grunwald F, Ruhlmann J, Kozak B, Overlack A, Christ F, Hotze A, Biersack H (1988) I-131 labeled metaiodobenzylguanidine in the diagnosis and treatment of distant metastases of a pheochromocytoma. Dtsch Med Wochenschr 113: 297–299
Käser H, (1985) Pathophysiologie und Klinik des Phaeochromocytoms und des Phaeochromoblastoms. In: Hauri D, Schmucki O (eds) Erkrankungen der Nebenschilddrüsen und Nebennieren. Fischer, Stuttgart, pp 195–207
Käser, H. (1987) Nebennierenmark-Funktion und -Störungen, In: Ziegler R (ed) Hormon-und Stoffwechselerkrankungen in der Praxis. Edition Medizin, Weinheim- Deerfield-Beach, Basel, pp 345–366
Käser H, Wagner HP (1982) Chromaffin tumors in childhood: experiences with 29 cases. In: Pediatric Oncology. Excerpta Medica, Amsterdam
Labhart A (1971) Das Nebennierenmark. In: Klinik der inneren Sekretion, Springer, Berlin Heidelberg New York
Langmann J (1970) Medizinische Embryologie. Thieme, Stuttgart
Manger WM, Gifford RW (1977) Pheochromocytoma. Springer, Berlin Heidelberg New York
McDougall IR (1984) Malignant pheochromocytoma treated by I-131 MIBG. J. Nucl. Med. 25: 249
Niklaus T (1986) Chromaffine Tumoren im Kindesalter. Inauguraldissertation, University of Berne, Switzerland
Otto R (1983) Die Sonographie der Nieren, der ableitenden Harnwege und der Nebennieren. Schweiz. Rundsch Med Prax 72: 227–232
Plouin PF, Duclos JM, Menard J, Comoy E, Bohuon C, Alexandre JM (1981) Biochemical tests for diagnosis of pheochromocytoma: urinary versus plasma determinations. Br Med J 282: 853–854
Robinson R (1980) Tumours that secrete catecholamines. Wiley, Chichester
Schmedtje JF, Sax S, Pool JL, Goldfarb RA, Nelson EB (1987) Localization of ectopic pheochromocytomas by magnetic-resonance imaging. J Med. 83: 770–772
Shapiro B, Copp JE, Sisson JC, Eyre PL, Beierwaltes WH (1985) 131–1 metaiodobenzyl-guanidine for the locating of suspected pheochromocytoma. Experience in 400 cases. J Nucl Med 26: 576–585
Shulkin BL, Shen SW, Sisson JC, Shapiro B (1987) Iodine-131 MIBG scintigraphy of the extremities in metastatic pheochromocytoma and neuroblastoma. J Nucl Med 28: 315–318
Stenström G, Svärdsudd K (1986) Pheochromocytoma in Sweden 1981–1985. Acta Med Scand 220: 225–232
Sutton MG St J, Sheps SG, Lie JT (1981) Prevalence of clinically unsuspected pheochromocytoma. Review of a 50-year autopsy series. Mayo Clin Proc 56: 354–360
Tippett PA, West RS, McEwan AJ, Middleton JE, Ackery DM (1987) A comparison of dopamine and homovanillic acid excretion, as prognostic indicators in malignant phaeochromocytoma. Clin. Chim. Acta 166: 123–133
Ziegler W (1985) Diagnostik des Phäochromocytoms. In: Hauri D, Schmucki O (eds) Erkrankungen der Nebenschilddrüsen und Nebennieren. Fischer, Stuttgart, pp 208–216
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Käser, H. (1990). Clinical and Diagnostic Findings in Patients with Chromaffin Tumors: Pheochromocytomas, Pheochromoblastomas. In: Beck, L., Grundmann, E., Ackermann, R., Röher, HD. (eds) Hormone-Related Malignant Tumors. Recent Results in Cancer Research, vol 118. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83816-3_10
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DOI: https://doi.org/10.1007/978-3-642-83816-3_10
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