The High Affinity Receptor for Immunoglobulin E: New Developments
Over the last few years considerable progress has been made in the field of the high affinity receptor for immunoglobulin E (FcεRI). The recent achievements were made possible by the rapid development of the techniques of molecular genetics. The cloning of complementary DNA for the rat a (Kinet et al 1987) (Shimizu et al 1988), the rat p (Kinet et al 1988), and the rat γ subunits (Blank et al 1989) of the receptor unveiled the respective DNA and amino-acid sequences of the subunits which became the basis for a new model of the receptor.
KeywordsHydrolysis Crystallization Carbohydrate Tyrosine Cysteine
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