Membrane Immunoglobulins Are Associated with a Family of Membrane Phosphoproteins

  • J. C. Cambier
  • K. S. Campbell
Conference paper


The immune response of B lymphocytes is regulated by a variety of soluble and cell-associated species including antigen, T cell-associated ligands such as CD4 and αβTcr, and a variety of lymphokines and other cytokines. These agents regulate B cell function via interaction with cell surface receptors which transduce information across the plasma membrane. Signal transduction involves receptor mediated activation of intracellular enzymes leading to generation of information carrying “second messenger” molecules.


Sodium Orthovanadate Aluminum Fluoride Kappa Chain Membrane Immunoglobulin Transmembrane Span Region 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. C. Cambier
  • K. S. Campbell

There are no affiliations available

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