The Development of B-Lymphomas in the Chicken
A few years ago, only a single B-cell tumor was known to develop in the chicken. Avian leukosis virus (ALV) induced a bursal-dependent B-lymphoma. The tumor appeared in 4 to 6 month old birds that had been infected on the day of hatch with ALV. We have recently described the development of two other B-cell lymphomas in the chicken. Their biological features and the molecular nature of the initial oncogenic events indicate that these tumors are distinct from each other and from the ALV-induced bursal-dependent lymphoma. It appears that the three tumors develop using different genetic pathways. In this report, I will discuss the biological differences between these tumors.
KeywordsMigration Lymphoma Testosterone Hematoxylin Eosin
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- Barth CF, Humphries EH (1989) Manuscript in preparation.Google Scholar
- Pizer E, Humphries EH (1989b) Avian B-cell lymphomas with insertionally mutated cmyb loci have heterogeneous expression of novel myb proteins. Submitted to J. Virol.Google Scholar
- Pizer E (1990) Ph.D. Thesis, Southwestern Graduate School, University of Texas, Dallas, TexasGoogle Scholar
- Purchase HG and Payne LN (1984) in Diseases of Poultry, eds. Hofstad MS, Barnes HJ, Calnek BW, Reid WM, Yoder HM. Iowa State Univ. Press, Ames IA. pp. 360–406Google Scholar