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Introduction to the Symposium on Complement

  • Conference paper
Progress in Immunology

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Abstract

It is the intention of this symposium to present the C system and to review some of its actual questions and not primarily to present the speakers’ own work. Along this line and due to the short space reserved for this introduction I will make reference primarily to reviews for further information of the reader and as a source of the original references.

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References

  • Atkinson MP, Farries T (1987) Separation of self from non-self in the complement system. Immunol Today 8:212–215

    Article  CAS  Google Scholar 

  • Bartholomew RM, Esser AF, MĂĽller-Eberhard HJ (1978) Lysis of oncornaviruses by human serum. Isolation of the viral complement (CI) receptor and identification as pl5E. J Exp Med 147:844–853

    Article  CAS  PubMed  Google Scholar 

  • Bitter-Suermann D, Hadding U, Schorlemmer HH, Limbert M, Dierich MP, Dukor P (1975) Activation by some T-independent antigens and B-cell mitogens of the alternative pathway of the complement system. J Immunol 115:42 5–430

    CAS  PubMed  Google Scholar 

  • Colten HR (1986) Molecular regulation of complement gene expression. In: Cinader B, Miller RG (Eds) Progress in Immunology VI. Academic Press, Orlando, p 314–324

    Chapter  Google Scholar 

  • Cooper NR, Nemerow GR (1983) Complement, viruses and virus-infected cells. Springer Semin Immunopathol 6:32 7–347

    Article  CAS  PubMed  Google Scholar 

  • Cooper NR, Moore MD, Nemerow GR (1988) Immunobiology of CR2, the B lymphocyte receptor for Epstein-Barr virus and the C3d complement fragment. Ann Rev Immunol 6:85–113

    Article  CAS  Google Scholar 

  • Cooper NR, Nemerow GR (1989) Complement and infectious agents: A tale of disguise and deception. Complement Inflamm 6:249–258

    CAS  PubMed  Google Scholar 

  • Dierich MP (1988) The receptors. In: Rother K, Till GO (Eds) The Complement System. Springer-Verlag, Berlin-Heidelberg, P 262–272

    Google Scholar 

  • Dierich MP, Erdei A, Huemer H, Petzer A, Stauder R, Schulz TF, Gergely J (1987) Involvement of complement in B-cell, T-cell and monocyte/macrophage activation. Immunol Lett 14:235–242

    Article  CAS  PubMed  Google Scholar 

  • Dierich MP, Huemer HP, Prodinger W (1989) C3-binding proteins of foreign origin. Curr Top Microbiol Immunol, in press

    Google Scholar 

  • Dierich MP, Schulz TF, Eigentler A, Huemer H, Schwäble W (1988) Structural and functional relationships among receptors and regulators of the complement system. Mol Immunol 25:1043–1051

    Article  CAS  PubMed  Google Scholar 

  • Friedman HM, Cohen GH, Eisenberg RJ, Seidel CA, Cines DB (1984) Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b complement component on infected cells. Nature 309:633–635

    Article  CAS  PubMed  Google Scholar 

  • Hammann KP, Raile A, Schmitt M, Mussel H, Peters H, Scheiner O, Dierich MP (1981) ĂźlH stimulates mouse-spleen B lymphocytes as demonstrated by increased thymidine incorporation and formation of B cell blasts. Immunobiol 160:289–301

    Article  CAS  Google Scholar 

  • Hänsch GM, Seitz M, Martinotti G, Betz M, Rauterberg EW, Gemsa D (1984) Macrophages release arachidonic acid, prostaglandin Eand thromboxane in response to late complement components. J Immunol 133:2145–2150

    PubMed  Google Scholar 

  • Joiner KA (1985) Studies on the mechanism of bacterial resistance to complement-mediated killing and on the mechanism of action of bactericidal antibody. Curr Top Microbiol Immunol 121:99–133

    CAS  PubMed  Google Scholar 

  • Kazatchkine MD, Dierich MP (1988) Human C3 complement receptor. In: Mani JC, Dornand J (Eds) Lymphocyte Activation and Differentiation. Walter de Gruyter, Berlin, p 765–779

    Google Scholar 

  • Kazatchkine MD, Fearon DT, Austen KF (1979) Human alternative complement pathway: Membran-associated sialic acid regulates the competition between B and ĂźlH for cell-bound C3b. J Immunol 122:75–89

    CAS  PubMed  Google Scholar 

  • Lambris JD (1988) The multifunctional role of C3, the third component of complement. Immunol Today 9:387–393

    Article  CAS  PubMed  Google Scholar 

  • Loos M (1982) The classical complement pathway: Mechanism of activation of the first component by antigen-antibody complex. Prog Allergy 30:135–192

    CAS  PubMed  Google Scholar 

  • Melchers F, Erdei A, Schulz TF, Dierich MP (1985) Growth control of activated, synchronized murine B cells by the C3 fragment of human complement. Nature 317: 264–267

    Article  CAS  PubMed  Google Scholar 

  • Melchers F, Erdei A, Corbel C, Leptin M, Schulz T, Dierich MP (1986) Cell cycle control of activated, synchronized murine B lymphocytes — roles of macrophages and complement C3. Mol Immunol 23:1173–1176

    Article  CAS  PubMed  Google Scholar 

  • MĂĽller-Eberhard HJ (1988) Molecular organization and function of the complement system. Ann Rev Biochem 57:321–347

    Article  PubMed  Google Scholar 

  • Nydegger UE, Kazatchkine MD (1986) Modulation by complement of immune complex processing in health and disease in man. Prog Allergy 39:361–392

    CAS  PubMed  Google Scholar 

  • Podack ER., Dennert G (1983) Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells. Nature 302:442–445

    Article  CAS  PubMed  Google Scholar 

  • Reid KBM, Day AJ (1989) Structure-function relationships of the complement components. Immunol Today 10:177–180

    Article  CAS  PubMed  Google Scholar 

  • Ross GD (1986) Immunobiology of the Complement System. Academic Press, Orlando

    Google Scholar 

  • Rother K and Rother U (1988) Herediatary and Acquired Complement Deficiencies in Animals and Man. Karger, Basel

    Google Scholar 

  • Rother K and Till GO (1988) The Complement System. Springer-Verlag, Berlin-Heidelberg

    Book  Google Scholar 

  • Soelder BM, Reisinger EC, Koefler D, Bitterlich G, Wächter H, Dierich MP (1989a) Complement receptors: Another port of entry for HIV-1. The Lancet, Juli 29, p. 271–272.

    Article  Google Scholar 

  • Soelder BM, Schulz TF, Hengster P, Löwer J, Larcher C, Bitterlich G, Kurth R, Wächter H, Dierich MP (1989b) HIV and HIV-infected cells differentially activate the human complement system independent of antibody. Immunol Letters, in press

    Google Scholar 

  • Weis JJ, Toothaker LE, Smith JA, Weis JH, Fearon DT (1988) Structure of the human B lymphocyte receptors for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins. J Exp Med 167:1047–1066

    Article  CAS  PubMed  Google Scholar 

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Authors
  1. M. P. Dierich
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Editor information

Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstrasse 487, 4005, Basel, Switzerland

    Fritz Melchers , H. von Boehmer  & L. Du Pasquier ,  & 

  2. Labor für Immungenetik, Kinderpoliklinik der Universität, Pettenkoferstrasse 8a, 8000, München 2, Germany

    E. D. Albert

  3. Institut für Hygiene, Universität Innsbruck und Ludwig Boltzmann-Institut für AIDS-Forschung, Fritz-Pregl-Strasse 3, 6010, Innsbruck, Austria

    M. P. Dierich

  4. Max-Planck-Institut fĂĽr Immunbiologie, StĂĽbeweg 51, 7800, Freiburg, Germany

    K. Eichmann

  5. Med.Zentrum fĂĽr Hygiene und Medizinische Mikrobiologie, Institut fĂĽr Immunologie, Robert-Koch-StraĂźe 8, 3550, Marburg, Germany

    D. Gemsa

  6. Abteilung Immunologie, Zentrum Hygiene und Humangenetik, Kreuzbergring 57, 3400, Göttingen, Germany

    O. Götze

  7. Institut und Poliklinik fĂĽr klinische Immunologie und Rheumatologie, KrankenhausstraĂźe 12, 8520, Erlangen, Germany

    J. R. Kalden

  8. Abt.Med.Mikrobiologie und Immunologie der Universität, Albert-Einstein-Allee 11, 7900, Ulm/Donau, Germany

    S. H. E. Kaufmann

  9. Institut fĂĽr Immunologie Transfusionsmedizin, Ratzeburger Allee 160, 2400, LĂĽbeck 1, Germany

    H. Kirchner

  10. Medizinische Hochschule Hannover Molekularpharmakologie, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Germany

    K. Resch

  11. Institut für Immunologie, Ludwig-Maximilians-Universität, Goethestrasse 31, 8000, München 2, Germany

    G. RiethmĂĽller

  12. Institut fĂĽr Virologie und Immunbiologie, Versbacher Strasse 7, 8700, WĂĽrzburg, Germany

    A. Schimpl

  13. Zentrum fĂĽr Dermatologie Institut fĂĽr Experimentelle Dermatologie, Von-Esmarch-Strasse 56, 4400, MĂĽnster, Germany

    C. Sorg

  14. F.Hoffmann-La Roche Co Ltd, ZFE, 4002, Basel, Switzerland

    M. Steinmetz

  15. Inst. fĂĽr Med. Mikrobiologie und Hygiene, TU MĂĽnchen Klinikum rechts der Isar, Trogerstrasse 9, 8000, MĂĽnchen 80, Germany

    H. Wagner

  16. Institut für Physiologische Chemie, Universität München, Goethestr. 33, 8000, München 2, Germany

    H. G. Zachau

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© 1989 Springer-Verlag Berlin Heidelberg

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Dierich, M.P. (1989). Introduction to the Symposium on Complement. In: Melchers, F., et al. Progress in Immunology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83755-5_22

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  • DOI: https://doi.org/10.1007/978-3-642-83755-5_22

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83757-9

  • Online ISBN: 978-3-642-83755-5

  • eBook Packages: Springer Book Archive

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