Abstract
Nosocomial bacterial infection is a major cause of morbidity and mortality in neonatal special care units. Numerous prospective and cross-sectional studies have investigated the prevalence of nosocomial paediatric infections and the factors causing high infection rates. Studies in North America [1, 2] and in Europe [3] have shown infection rates ranging from 10 to 30% of all admissions. In addition, outbreaks involving specific pathogens may cause higher infection rates over a limited time. In many cases of nosocomial infection, particularly those due to gram-negative bacteria, the problem is increased by antibiotic-resistant pathogens, leading to treatment failures or to the use of antimicrobial agents with narrow efficacy/toxicity ratios in infants.
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© 1989 Springer-Verlag Berlin Heidelberg
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Shears, P., Leonard, M., Walker, J. (1989). Where and How Does Antimicrobial Resistance Develop in the Critically Ill? Studies in Neonatal Patients. In: van Saene, H.K.F., Stoutenbeek, C.P., Lawin, P., Ledingham, I.M. (eds) Infection Control in Intensive Care Units by Selective Decontamination. Update in Intensive Care and Emergency Medicine, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83752-4_18
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DOI: https://doi.org/10.1007/978-3-642-83752-4_18
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-51041-3
Online ISBN: 978-3-642-83752-4
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