Erythropoietin Production in Malignancy

  • H. Johannsen
  • A. J. Gross
  • W. Jelkmann


The glycoprotein hormone erythropoietin stimulates the proliferation and differentiation of erythrocytic progenitors in bone marrow. Erythropoiesis counterbalances the permanent loss of aged red blood cells. The red cell mass, hemoglobin concentration, and oxygen transport capacity of the blood are relatively constant under physiological conditions. The production of erythropoietin is augmented following phlebotomy, until the mass of red blood cells is restored.


Chronic Myelogenous Leukemia Acute Myelogenous Leukemia Human Renal Carcinoma Cell Erythropoietin Level Acute Myelogenous Leukemia Patient 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • H. Johannsen
  • A. J. Gross
  • W. Jelkmann

There are no affiliations available

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