Management of Advanced Local Disease
This chapter discusses the patients in whom the extent of the primary tumor is such that there can be little chance of cure. Twenty years ago, Cutler produced data on patients with cancer of the breast, relating the clinical stage to subsequent survival. Patients with overt distant metastatic disease, fixed axillary lymph nodes, or edema of the skin of the breast, were not included. The series did include larger tumors, often with skin involvement and attachment to the underlying pec-toralis muscles.
KeywordsEstrogen Oncol Tamoxifen Progesterone Carbone
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