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Katatone und dyskinetische Syndrome pp 127–143Cite as

Zur Therapie von Dystonien und Athetosen

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Zusammenfassung

Unter Dystonie versteht man langsame, unwillkürliche Kontraktionen vorwie gend der proximalen Muskulatur, die oft zu rotierenden Bewegungen und bizarren Gelenkstellungen sowie Körperpositionen führen. Die Dystönien werden nach Marsden (1982) unterteilt in: 1. fokale Dystönien, falls nur eine einzelne Region betroffen ist (z. B. Nacken oder Gesicht), 2. segmentale Dystönien, wenn ein Segment bilateral (z. B. beide Arme) oder wenn zwei oder drei benachbarte Körperabschnitte betroffen sind (z. B. Gesicht und Nacken) und 3. generalisierte Dystönien, falls ein Arm und Bein der jeweils anderen Seite oder mehr als drei Segmente betroffen sind (Fahn 1983). Aufgrund der symptomatischen Dystonien beim M. Wilson und Befunden bei perinatalen Schädigungen mit Dystonie wird eine Läsion der Basalganglien angenommen.

Eine frühere Fassung dieses Artikels findet sich in Brandt T, Dichgans J. und Diener H.C. (1987) Therapie und Verlauf neurologischer Erkrankungen. Kohlhammer, Stuttgart.

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Literatur

  • Altrocchi PM (1972) Spontaneous oral-facial dsykinesia. Arch Neurol 28:506–512

    Article  Google Scholar 

  • Andrew J, Fowler CJ, Harrison MJG (1983) Stereotaxic thalamotomy in 55 cases of dys tonia. Brain 106:981–1000

    Article  PubMed  Google Scholar 

  • Ansari KA, Webster D, Manning N (1972) Spasmodic torticollis and L-Dopa. Neurology 22:670–674

    PubMed  CAS  Google Scholar 

  • Asher SW, Aminoff MJ (1981) Tetrabenazine and movement disorders. Neurology 31:1051–1055

    PubMed  CAS  Google Scholar 

  • Barbeau A (1976) General discussion of drug therapy in dystonia. In: Elridge R, Fahn S (eds) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 417–422

    Google Scholar 

  • Bartels M, Zeller E (1984) Tetrabenazine (Nitoman) therapy of chronic spontaneous oral dyskinesia. A video-and EMG-controlled study. Eur Arch Psychiatr Neurol Sei 234:172–174

    Article  CAS  Google Scholar 

  • Bassi S, Ferrarese C, Frattola L, Sbacchi M, Trabucchi M (1982) Lisuride in generalized dys tonia and spasmodic torticollis. Lancet I: 514–515

    Google Scholar 

  • Battista AF (1983) Surgical therapy for blepharospasm. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurology, Vol 37. Raven, New York, pp 215–224

    Google Scholar 

  • Bertrand C, Molina-Negro P, Bouvier G, Gorczyca W (1987) Observations and analysis of results in 131 cases of spasmodic torticollis after selective denervation. Appl Neurophysiol 50:319–323

    PubMed  CAS  Google Scholar 

  • Bird AC, McDonald WI (1975) Essential belpharospasm. Trans Ophthal Soc UK 95:250–253

    PubMed  CAS  Google Scholar 

  • Brennan MJW, Ruff P, Sandy KR (1982) Efficacy of a combination of sodium valproate and baclofen in Meige’s disease (idiopathic orofacial dystonia). Br Med J 285:853

    Article  CAS  Google Scholar 

  • Brinkmann A, Schumm F, Dichgans J (1985) Therapie des Meige-Syndroms. In: Gänshirt H, Berlit P, Haack G (Hrsg) Kardiovaskuläre Erkrankungen und Nervensystem -Neurotoxikologie -Probleme des Hirntodes. Verhandlungen der Deutschen Gesellschaft für Neurologie, Bd 3. Springer, Berlin Heidelberg New York Tokyo, S 662–666

    Google Scholar 

  • Casey DE (1980) Pharmocology of blepharospasm oromandibular dystonia syndrome. Neurology 30:690–695

    PubMed  CAS  Google Scholar 

  • Cavenar JO, Brantley IJ, Braasch E (1978) Blepharospasm: Organic or funcitonal? Psychosomatics 19:623–628

    PubMed  Google Scholar 

  • Claus D, Aschoff JC (1979) Behandlung extrapyramidaler Bewegungsstörungen mitTiaprid. Arch Psychiat Nervenkr 227:151–158

    PubMed  CAS  Google Scholar 

  • Cleeland CS (1973) Behavioural technics in the modification of spasmodic torticollis. Neurology 23:1241–1247

    PubMed  CAS  Google Scholar 

  • Cooper IS (1976) 20-year follow-up study of the neurosurgical treatment of dystonia mus-culorum deformans. In: Elridge R, Fahn S (eds) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 423–452

    Google Scholar 

  • Couch JR (1976) Dystonia and tremor in spasmodic torticollis. In: Elridge R, Fahn S (eds) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 245–258

    Google Scholar 

  • Dahdaleh M, Small M, Thomas DJ (1975) Dimetyl aminoethanol in blepharospasm and hemifacial spasm. N Engl J Med 293:98

    PubMed  CAS  Google Scholar 

  • Delwaide PJ, Desseiles M (1977) Spontaneous buccolignofacial dyskinesia in the elderly. Acta Neurol Scand 56:256–262

    Article  PubMed  CAS  Google Scholar 

  • Dowling-Bruun R (1984) Gilles de la Tourette’s syndrome. J Am Acad Child Psychiatry 23:126–133

    Article  Google Scholar 

  • Eldrigde R, Gottlieb R (1976) The primary hereditary dystonias: Genetic classification of 786 families and revised estimate of gene frequency, autosomal recessive form, and selected bibliography. Adv Neurol 14:457–474

    Google Scholar 

  • Erenberg G, Cruse RP, Rothner AD (1987) The natural history of Tourette syndrome: A follow up study. Ann Neurol 22:383–385

    Article  PubMed  CAS  Google Scholar 

  • Fahn S (1982) Torsion dystonia: Clinical spectrum and treatment. Sem Neurol 2:316:323

    Article  Google Scholar 

  • Fahn S (1983 a) High-dosage anticholinergic therapy in dystonia. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurol ogy, Vol 37. Raven, New York, pp 177–188

    Google Scholar 

  • Fahn S (1983 b) High dosage anticholinergic therapy in dystonia. Neurology 33:1255–1261

    PubMed  CAS  Google Scholar 

  • Foley J (1983) The athetoid syndrome. A review of a personal series. J Neurol Neurosurg Psychiatry 46:289–298

    Article  PubMed  CAS  Google Scholar 

  • Frueh BR, Callahan A, Dortzbach RK, Wilkins RB, Beale HL, Reitman HS, Watson FR (1974) The effects of differential section of the Vllth nerve on patients with intractable blepharospasm. Trans Am Acad Ophthalmol Otolaryngol 81:595–602

    Google Scholar 

  • Gautier JC, Awada A (1983) Dystonia musculorum deformans. Effet favorable de la bromocriptine. Rev Neurol 139:449–450

    PubMed  CAS  Google Scholar 

  • Geller M, Kaplan B, Christoff N (1976) Treatment of dystonic symptoms with carbamazepine. In: Elridge R, Fahn S (eds) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 403–410

    Google Scholar 

  • Gerber WD (1986) Neurologische Störungen. In: Miltner W, Bierbaumer N, Gerber WD (Hrsg) Verhaltensmedizin. Springer, Berlin Heidelberg New York Tokyo, S 386–428

    Google Scholar 

  • Girotti F, Scigliano G, Nardocci N, Angelini L, Broggi G, Giovanni P, Caraceni T (1982) Idopathic dystonia: Neuropharmacological study. J Neurol 227:239–247

    Article  PubMed  CAS  Google Scholar 

  • Gollomp SM, Fahn S, Burke RE, Reches A, Ilson J (1983) Therapeutic trials in Meige syndrome. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurology, Vol 37. Raven, New York, pp 207–213

    Google Scholar 

  • Goodwin-Austen RB, Clark T (1971) Persistent phenothiazine dyskinesia treated with tetrabenazine. Br Med J 4:25–26

    Article  Google Scholar 

  • Hagenah R, Habich C, Müller D (1983 a) Medikamentöse Therapie des Torticollis spasmodicus. Psycho 9:319–320

    Google Scholar 

  • Hagenah R, Habich C, Müller D, Freckmann N (1983 b) Subjektive Beurteilung der Wirkung operativer Therapieverfahren beim Torticollis spasmodicus. Psycho 9:320–321

    Google Scholar 

  • Henderson JW (1956) Essential blepharospasm. Trans Am Ophthalmol Soc 54:453–520

    PubMed  CAS  Google Scholar 

  • Houten R ten, Lakke JPWF, de Jong P, van Wesseling TW, van den Burg W, Wesseling H (1984) Spasmodic torticollis: Treatment with tizanidine. Acta Neurol Scand 70:373–376

    Article  PubMed  Google Scholar 

  • Isgreen WP, Fahn S, Barrett RE, Snider SR, Chutorian AM (1976) Carbamazepine in torsion dystonia. In: Elridge R, Fahn S (Hrsg) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 411–416

    Google Scholar 

  • Jankovic J (1982) Treatment of hyperkinetic movement disorders with tetrabenazine: A double blind crossover study. Ann Neurol 11:41–47

    Article  PubMed  CAS  Google Scholar 

  • Jankovic J. (1983) Tetrabenazine in the treatment of hyperkinetic movement disorders. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurology, Vol 37. Raven, New York, pp 283–289

    Google Scholar 

  • Jankovic J, Ford J (1983) Blepharospasm and orofacial-cervical dystonia: Clinical and pharmacological findings in 100 patients. Ann Neurol 13:402–411

    Article  PubMed  CAS  Google Scholar 

  • Jayne D, Lees AJ, Stern GM (1984) Remission in spasmodic torticollis. J Neurol Neurosurg Psychiatry 47:1236–1237

    Article  PubMed  CAS  Google Scholar 

  • Juntunen J, Kaste M, Ivanainen M, Ranta T, Seppälä M (1979) Bromocriptine treatment of spasmodic torticollis. Arch Neurol 36:449–450

    Article  PubMed  CAS  Google Scholar 

  • Koller WC, Barr A, Biarry N (1982) Estrogen treatment of dyskinetic disorders. Neurology 32:547–549

    PubMed  CAS  Google Scholar 

  • Korein J, Brudny J, Grynbaum B, Sachs-Frankel G, Weisinger M, Levidow L (1976) Sensory feedback therapy of spasmodic torticollis and dystonia: Results in treatment of 55 pa tients. In: Elridge R, Fahn S (eds) Dystonia. Advances in Neurology, Vol 14. Raven, New York, pp 375–402

    Google Scholar 

  • Korein J, Liebermann A, Kupersmith M, Levidow L (1981) Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. Ann Neurol 10:247–250

    Article  PubMed  CAS  Google Scholar 

  • Leiguarda RC, Pardal MF, Micheli F (1984) Reply from the author. Neurology 34:136

    Google Scholar 

  • Leplow B, Lamparter U, Hagenah R (1983) Teilstationäre sensorische Feedbacktherapie des Torticollis spasmodicus. Psycho 9:312–321

    Google Scholar 

  • Marinello C, Baumberger K, Fisch U (1979) Langzeitresultate der chirurgischen Therapie von Spasmus hemifacialis und Blepharospasmus. HNO 27:54–57

    PubMed  CAS  Google Scholar 

  • Marsden CD (1982) The focal dystonias. Sem Neurol 2:324–333

    Article  Google Scholar 

  • Marsden CD, Harrison MJG (1974) Idiopathic torsion dystonia. Brain 97:793–810

    Article  PubMed  CAS  Google Scholar 

  • Marsden CD, Marion MH, Quinn N (1984) The treatment of severe dystonia in children and adults. J Neurol Neurosurg Psychiatry 47:166–1173

    Google Scholar 

  • MesulamWM, Petersen RC (1987) Treatment of Gilles de laTourette syndrome. Neurology 37:1828–1833

    PubMed  CAS  Google Scholar 

  • Micheli F, Pardal MMF, Leiguarda RC (1982) Beneficial effects of lisuride in Meige disease. Neurology 32:432–434

    PubMed  CAS  Google Scholar 

  • Miller E (1973) Demethyl aminoethanol in the treatment of blepharospasm. N Engl J Med 289:697

    PubMed  CAS  Google Scholar 

  • Mitscherlich M (1983) Zur Theorie und Therapie des Torticollis. In: Studt HH (Hrsg) Psychosomatik in Forschung und Praxis. Urban & Schwarzenberg, München

    Google Scholar 

  • Muenter MD, Gomez MR, Gordon H, Sharpless NS (1982) L-doparesponsive dystonia musculorum deformans with on-off effect. Neurology 32:A 112

    Google Scholar 

  • Niewold JUR, Drentje B, Weerden TW, Lakke JPWF (1985) Biofeedback in the management of spasmodic torticollis. J Neurol 232 (Suppl):234

    Google Scholar 

  • Nutt JG, Hammerstad JP, Carter JH, DeGarmo P (1983) Meigesyndrome: Treatment with trihexy-phenidyl. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurology, Vol 37. Raven, New York, pp 201–205

    Google Scholar 

  • Nutt JG, Hammerstad JP, DeGarmo P, Carter JH (1984) Cranial dystonia: Double-blind crossover study of anticholinergics. Neurology 34:215–217

    PubMed  CAS  Google Scholar 

  • Nutt JG, Hammerstad JP, Carter JH, DeGarmo PL (1985) Lisuride treatment of focal dystonias. Neurology 35:1242–1243

    PubMed  CAS  Google Scholar 

  • Obeso JA, Luquin MR (1984) Bromocriptine and lisuride in dystonias. Neurology 34:135

    PubMed  CAS  Google Scholar 

  • Pakkenberg H, Fog R (1974) Spontaneous oral dyskinesia. Arch Neurol 31:352–353

    Article  PubMed  CAS  Google Scholar 

  • Paulson GW (1972) Meige’s syndrome. Dyskinesia of the eyelids and facial muscles. Geriatrics 27:69–73

    PubMed  CAS  Google Scholar 

  • Przuntek H, Monninger P (1983) Therapeutic aspects of kinesiogenic paroxysmal choreaathetosis and familial paroxysmal choreaathetosis of the Mount and Reback type. J Neurol 230:163–169

    Article  PubMed  CAS  Google Scholar 

  • Quinn N, Marsden CD (1984) A double blind trial of sulpiride in Huntington’s disease and tardive dyskinesia. J Neurol Neurosurg Psychiatry 47:844–847

    Article  PubMed  CAS  Google Scholar 

  • Regeur L, Pakkenberg B, Fog R, Pakkenberg H (1986) Clinical features and long-term treatment with pimozide in 65 patients with Gilles de la Tourette’s syndrome. J Neurol Neurosurg Psychiatry 49:791–795

    Article  PubMed  CAS  Google Scholar 

  • Rentrop E, Straschill M (1982) Verlaufsformen des idiopathischen Torticollis spasmodicus. Aktuel Neurol 9:150–154

    Article  Google Scholar 

  • Richards CL, Bédard PJ, Fortin G, Malovin F (1983) Quantitative evaluation of the effects of L-dopa in torsion dystonia: A case report. Neurology 33:1083–1087

    PubMed  CAS  Google Scholar 

  • Schneider R, Buchan AP, Couston TA (1976) Low-dosage treatment withTetrabenazine. Br Med J I: 1212

    Article  Google Scholar 

  • Schumm F, Dichgans J, Zeller E (1981) Spontane orale dyskinesien. Erfolgreiche Therapie mit Tetrabenazin (Nitoman). Arch Psychiatr Nervenkr 230:315–323

    Article  PubMed  CAS  Google Scholar 

  • Scott AB, Kennedy RA, Harrison AS (1985) Botulinum A toxin injection as a treatment for blepharospasm. Arch Ophthalmol (Chicago) 103:347–350

    CAS  Google Scholar 

  • Shorr N, Seiff SR, Kopelman J (1985) The use of botulinum toxin in blepharospasm. Am J Ophthalmol 99:542–546

    PubMed  CAS  Google Scholar 

  • Singer K, Cheng MN (1971) Thiopropazate hydrochloride in persistent dyskinesia. Br Med J 4:22–25

    Article  PubMed  CAS  Google Scholar 

  • Snoek JW, Weerden TW van, Teelken AW, Burg W van den, Lakke JP (1987) Meige syn drome: Double-blind crossover study of sodium valproate. J Neurol Neurosurg Psychiatry 50:1522–1525

    Article  PubMed  CAS  Google Scholar 

  • Sörensen BF, Hamby WB (1966) Spasmodic torticollis. Results in 71 surgically treated patients. Neurology 16:867–878

    Google Scholar 

  • Stahl SM, Berger PA (1971) Bromocriptine in dystonia. Lancet II: 745

    Google Scholar 

  • Stahl SM, Berger PA (1982) Effects of bromocriptine and physostigmine in the dystonias. Neurology 32: A 112

    Google Scholar 

  • Stahl SM, Yesavage JA, Berger PA (1982) Pharmacologic characteristics of Meige dystonia: Differentiation from tardive dyskinesia. J Clin Psychiatry 43:445–446

    PubMed  CAS  Google Scholar 

  • Stober T, Anstatt T, Schimrigk KK (1983) Erfolgreiche Isoniazid-Therapie bei athetotischem Syndrom. Nervenarzt 54:658–659

    PubMed  CAS  Google Scholar 

  • Swash M, Roberts AH, Zakko H, Heathfield KWG (1972( Treatment of involuntary movement disorder with tetrabenazine. J Neurol Neurosurg Psychiatry 35:186–191

    Article  PubMed  CAS  Google Scholar 

  • Talbot JF, Gregor Z, Bird AC (1982) The surgical management of essential blepharospasm. In: Marsden CD, Fahn S (eds) Movement disorders. Butterworth, London, pp 322–329

    Google Scholar 

  • Tanner CM, Glantz RH, Klawans HL (1981) Meige syndrome (blepharospasm oromandibular dystonia syndrome): Analysis of the clinical pharmacology in 12 patients. Neurology 31:78

    Google Scholar 

  • Tanner CM, Glantz RH, Klawans HL (1982) Meige disease: Acute and chronic cholinergic effects. Neurology 32:783–785

    PubMed  CAS  Google Scholar 

  • Toglia JU, McGlamery M, Sambandham RR (1978) Tetrabenazine in the treatment of Huntingtons chorea and other hyperkinetic movement disorders. J Clin Psychiatry 39:81–87

    PubMed  CAS  Google Scholar 

  • Tolosa ES (1981) Clinical features of Meige’s disease (idiopathic orofacial dystonia). Arch Neurol 38:147–151

    Article  PubMed  CAS  Google Scholar 

  • Tolosa ES, Lai CW (1979) Meige disease. Striatal dopaminergic preponderance. Neurology 29:1126–1130

    PubMed  CAS  Google Scholar 

  • Vizioli R, Dicerbo M, Vigliotti MR (1985) Familial paroxismal choreoathetosis. J Neurol 232 (Suppl) 235

    Google Scholar 

  • Waltz JM, Davis JA (1983) Cervical cord stimulation in the treatment of athetosis and dystonia. In: Fahn S, Calne DB, Shoulson I (eds) Experimental therapeutics of movement disorders. Advances in Neurology, Vol 37. Raven, New York, pp 225–237

    Google Scholar 

  • Weingarten CZ, Putterman AM (1976) The management of patients with essential blepharospasm. Eye Ear Nose Throat Monthly 55:8–24

    PubMed  CAS  Google Scholar 

  • Zeman W, Dyken P (1968) Dystonia musculorum deformans. In: Vinken PJ, Bruyn GW(eds) Diseases of the basal ganglia. Handbook of clinical neurology, Vol 6. North Holland Publ, Amsterdam, pp 517–543

    Google Scholar 

  • Ziegler DK (1981) Prolonged relief of dystonic movements with diazepam. Neurology 31:1457–1458

    PubMed  CAS  Google Scholar 

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Authors
  1. J. Dichgans
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  2. A. Brinkmann
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Editors and Affiliations

  1. Psychiatrischen Klinik und Poliklinik der Universität München, Nußbaumstraße 7, D-8000, München 2, Deutschland

    Hanns Hippius (Direktor der Psychiatrischen Klinik und Poliklinik der Universität München) (Direktor der Psychiatrischen Klinik und Poliklinik der Universität München)

  2. Psychiatrischen Klinik der Universität Göttingen, v.-Siebold-Straße 5, D-3400, Göttingen, Deutschland

    Eckart Rüther (Direktor der Psychiatrischen Klinik der Universität Göttingen) (Direktor der Psychiatrischen Klinik der Universität Göttingen)

  3. Psychiatrische Klinik und Poliklinik der Universität München, Nußbaumstraße 7, D-8000, München 2, Deutschland

    Max Schmauss (Oberarzt) (Oberarzt)

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Dichgans, J., Brinkmann, A. (1989). Zur Therapie von Dystonien und Athetosen. In: Hippius, H., Rüther, E., Schmauss, M. (eds) Katatone und dyskinetische Syndrome. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83654-1_13

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