Abstract
Summary: The locomotion of the body’s component cells depends upon the formation of three classes of protrusions from the cell surface. These protrusions have been studied primarily in tissue culture, where they all form preferentially along the leading margins of crawling cells. They differ from one another in shape: flattened protrusions are called “lamellipodia” (or “ruffles”); rounded protrusions are called “lobopodia” (or “blebs”); while the third class consists of narrow, stiff rods called “filopodia” (or “microspikes”). These are actively pushed out from the cell surface, although some then form adhesions to the substratum or to other cells.
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Harris, A.K. (1990). Protrusive Activity of the Cell Surface and the Movements of Tissue Cells. In: Akkaş, N. (eds) Biomechanics of Active Movement and Deformation of Cells. NATO ASI Series, vol 42. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83631-2_9
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DOI: https://doi.org/10.1007/978-3-642-83631-2_9
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