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The Mechanics of Morphogenesis in Multicellular Embryos

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Book cover Biomechanics of Active Movement and Deformation of Cells

Part of the book series: NATO ASI Series ((ASIH,volume 42))

Abstract

Our subject is morphogenesis, the shaping of a multicellular embryo. As an embryo develops, it acquires sequentially the characteristic levels of biological organization: A single cell, a fertilized egg, generates a mass of cells which form tissues, then organs, then organ systems. Processes at all of these levels depend on each other; to understand morphogenesis one must unravel this interdependence. The major subject of current investigations in cell biomechanics is the relation between activities of cells and the molecular processes that mediate these activities. In these investigations most experiments focus on the behavior of single cells, or on the interactions between pairs of cells. However, such studies leave unresolved the many-cell problem: How do many cells, interacting in diverse ways, shape an embryo?

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Authors and Affiliations

  1. Department of Cell and Structural Biology, University of Illinois, 505 S. Goodwin St., Urbana, Illinois, 61801, USA

    Jay E. Mittenthal

  2. Department of Zoology, Center for Developmental Biology, University of Texas, Austin, Texas, 78712, USA

    Antone G. Jacobson

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  1. Jay E. Mittenthal
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  1. Department of Engineering Sciences, Middle East Technical University, 06502, Ankara, Turkey

    Nuri Akkaş

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Mittenthal, J.E., Jacobson, A.G. (1990). The Mechanics of Morphogenesis in Multicellular Embryos. In: Akkaş, N. (eds) Biomechanics of Active Movement and Deformation of Cells. NATO ASI Series, vol 42. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83631-2_10

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  • DOI: https://doi.org/10.1007/978-3-642-83631-2_10

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