Bone Regeneration with Collagen-Apatite and Mineral Bone

  • B.-D. Katthagen
  • H. Mittelmeier


Hydroxyapatite (HA) has been proven by numerous authors to be excellently biocompatible and bioactive. Bone ingrowth into porous HA, however, depends on pore size. As we could show by own experiments, low-porosity HA exhibits perfect bone ongrowth but only marginal ingrowth. An implant with small pores acts as a barrier and hinders rather than promotes bone healing of the defect.


Bone Regeneration Bone Substitute Bone Repair Bone Ingrowth Benign Bone Tumour 
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  1. 1.
    Katthagen B-D (1987) Bone regeneration with bone substitutes. Springer, Berlin Heidelberg New YorkCrossRefGoogle Scholar

Copyright information

© Springer-Verlag, Berlin Heidelberg 1989

Authors and Affiliations

  • B.-D. Katthagen
    • 1
  • H. Mittelmeier
    • 1
  1. 1.Orthopaedic University HospitalHomburgGermany

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