Advertisement

Nervous System pp 101-103 | Cite as

Tellurium Poisoning, Rat

  • Kenneth R. Reuhl
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)

Abstract

In the congenital form of tellurium poisoning, the principal effects visible to the naked eye are paralysis and hydrocephalus. In the adult, acute toxicity due to tellurium does not result in any gross lesions. Chronic toxicity results in diffuse, dark gray discoloration of the cerebral cortex.

Synonym

Tellurism 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Braheny SL, Lampert PW (1980) Tellurium. In: Spencer PS, Schaumburg HH (eds) Experimental and clinical neurotoxicology. Williams and Wilkins, Baltimore, pp 558–569Google Scholar
  2. Duckett S (1971) The morphology of tellurium-induced hydrocephalus. Exp Neurol 31:1–16CrossRefPubMedGoogle Scholar
  3. Duckett S, White R (1974) Cerebral lipofuscinosis induced with tellurium. Electron dispersive X-ray spectrophotometry analysis. Brain Res 73: 205–214CrossRefPubMedGoogle Scholar
  4. Garro F, Pentschew A (1964) Neonatal hydrocephalus in the offspring of rats fed during pregnancy non-toxic amounts of tellurium. Arch Psychiatr Nervenkr 206: 272–280Google Scholar
  5. Hollins JG (1969) The metabolism of tellurium in rats. Health Phys 17: 497–505CrossRefPubMedGoogle Scholar
  6. Lampert PW, Garrett MS (1971) Mechanism of demyelination in tellurium neuropathy. Electron microscopic observations. Lab Invest 25: 380–388PubMedGoogle Scholar
  7. Lampert P, Garro F, Pentschew A (1970) Tellurium neuropathy. Acta Neuropathol (Berl) 15: 308–317CrossRefPubMedGoogle Scholar
  8. Miyoshi K, Takauchi S (1977) Chronic tellurium intoxication in rats. Folia Psychiatr Neurol Jpn 31:111–118PubMedGoogle Scholar
  9. Spencer PS, Foster GF, Sterman AB, Horoupian D (1979) Acetyl ethyl tetramethyl tetralin. In: Spencer PS, Schaumberg HH (eds) Experimental and clinical neurotoxicology. Williams and Wilkins, Baltimore, pp 296–308Google Scholar
  10. Yeun TG, Agnew WF, Carregal EJ (1975) Lysosomal handling of tellurium by the choroid plexus following chronic administration: an ultrastructural study. Exp Neurol 47:213–228CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • Kenneth R. Reuhl

There are no affiliations available

Personalised recommendations