Skip to main content

Neurotoxicity of Perhexiline Maleate in Rats

  • Chapter
Nervous System

Abstract

No remarkable feature is seen by gross examination in the brain, spinal cord, or peripheral ganglia.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Hayashi Y, Otsuka H, Yoshimura S, Seki T, Ono H, Hashimoto K (1981 a) Acute toxicity of perhexiline in rats and mice. Pharmacometrics Oyo Yakuri 21: 83–94

    CAS  Google Scholar 

  • Hayashi Y, Yoshimura S, Yamaguchi K, Imai K, Abe F, Ono H, Hashimoto K (1981b) Subacute toxicity of perhexiline in rats. Pharmacometrics Oyo Yakuri 21: 95–122

    CAS  Google Scholar 

  • Jung HJ, Suzuk K (1978) Morphological changes in CNS of rats treated with perhexiline maleate (Pexid). Acta Neuropathol (Berl) 42: 159–164

    Article  CAS  PubMed  Google Scholar 

  • Lhermitte F, Fardeau M, Chedru F, Mallecourt J (1976) Polyneuropathy after perhexiline maleate therapy. Br Med J 1:1256

    Article  CAS  PubMed  Google Scholar 

  • Lüllmann H, Lüllmann-Rauch R, Wassermann O (1975) Drug-induced phospholipidosis. II. Tissue distribution of the amphiphilic drug chlorphentermine. CRC Crit Rev Toxicol 4:185–218

    PubMed  Google Scholar 

  • Lüllmann H, Lüllman-Rauch R (1978) Perhexiline induced generalized lipidosis in rats. Klin Wochenschr 56: 309–310

    Article  PubMed  Google Scholar 

  • Robinson BF (1977) Drugs acting on the cardiovascular system. In: Dukes MNG (ed) Side effects of drugs annual, vol I. Elsevier North Holland, pp 151–163

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hyashi, Y., Maekawa, A., Yoshimura, S. (1988). Neurotoxicity of Perhexiline Maleate in Rats. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Nervous System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83516-2_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83516-2_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83518-6

  • Online ISBN: 978-3-642-83516-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics