Cardiac Involvement in Kearns-Sayre Syndrome

  • B. Schwartzkopff
  • G. Breithardt
  • M. Borggrefe
  • B. Lösse
  • K.-V. Toyka
  • H. Frenzel
Conference paper


Progressive external ophthalmoplegia (PEO) is accompanied by a progressive weakness of the external muscles of the eyes. It was first described by Albrecht von Graefe in 1866 [20]. First believed to be of neurogenic origin, it was not until 1951 that Kiloh and Nevin [30] suggested that the ocular signs were due to a myopathy as they in one case found histological abnormalities in the medial rectus muscle.


Cardiac Involvement Atrial Pace Mitochondrial Myopathy Versus Block Progressive External Ophthalmoplegia 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • B. Schwartzkopff
  • G. Breithardt
  • M. Borggrefe
  • B. Lösse
  • K.-V. Toyka
  • H. Frenzel

There are no affiliations available

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