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Abnormal Coronary Vasomotion in the Genesis of Transient Myocardial Ischemia

  • J. C. Kaski
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 6)

Abstract

The vital role of coronary arteries was clearly demonstrated by the end of the 17th century, when Chirac occluded one of these vessels and provoked the death of the experimental animal [1]. The function of coronary arteries is dependent upon their vasomotion, and the possibility of altering its caliber is related to the mechanics of the smooth muscle in the wall of the artery. Under resting conditions these arteries are only moderately compliant as shown by Klassen et al. [2]. However, clinical observations and experimental studies have indicated that coronary epicardial vessels may experience intense spasm [3–8] which may lead to ischemic damage of the heart muscle and severe myocardial dysfunction [9, 10].

Keywords

Myocardial Ischemia Coronary Flow Coronary Flow Reserve Coronary Blood Flow Chronic Stable Angina 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

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  • J. C. Kaski

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