The Effect of Intrathoracic Pressure on the Failing Heart

  • M. R. Pinsky
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 6)


Although it has been appreciated for centuries that under normal conditions increases in intrathoracic pressure (ITP) decrease cardiac output [1], only recently has it been realized that in the failing heart similar increases in ITP may have a different effect [2]. Over the past thirty years, our understanding of the effect of increasing ITP on the failing heart has greatly increased. This report will discuss selective aspects of the recent data on the effects of ITP on left ventricular (LV) function and cardiac output during heart failure.


Right Ventricle Intrathoracic Pressure Left Ventricular Filling Pressure Ventricular Stroke Volume Left Ventricular Afterload 
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© Springer-Verlag Berlin Heidelberg 1988

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  • M. R. Pinsky

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