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The Place of Phosphodiesterase Inhibitors

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Acute Heart Failure

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 6))

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Abstract

Myocardial contractility can be increased by various mechanisms other than those exerted by digitalis or adrenergic agents. The so-called non-digitalis, nonadrenergic agents actually encompass a wide variety of substances among which drugs supposed to act by inhibition of the myocardial phosphodiesterase (type III) appear most promising. Phosphodiesterase (PDE) inhibitors act to increase intracellular cyclic adenosine monophosphate (AMP) concentration.

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Authors
  1. J. L. Vincent
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Editors and Affiliations

  1. Department of Intensive Care, C. H. U. Vaudois, CH-1011, Lausanne, Switzerland

    Claude Perret (Director) (Director)

  2. Department of Intensive Care, Erasme University Hospital, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean Louis Vincent (Assistant-Director) (Assistant-Director)

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© 1988 Springer-Verlag Berlin Heidelberg

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Vincent, J.L. (1988). The Place of Phosphodiesterase Inhibitors. In: Perret, C., Vincent, J.L. (eds) Acute Heart Failure. Update in Intensive Care and Emergency Medicine, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83453-0_18

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  • DOI: https://doi.org/10.1007/978-3-642-83453-0_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-19169-8

  • Online ISBN: 978-3-642-83453-0

  • eBook Packages: Springer Book Archive

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