Oxidative Metabolism of Unsaturated Fatty Acids and Free Radical Formation
Our interest in the metabolism of C22 fatty acids, both mono- and polyunsaturated, started around 1970. In that year Abdellatif and Vies  published their study showing that feeding great amounts of rapeseed oil containing the monounsaturated erucic acid (C22:1) to rats caused acute lipidosis of the heart. Later a Canadian group showed that hydrogenated fish oil to some degree had the same effect . The fat infiltration proved to be temporary. If the feeding of these fats is continued the fat infiltration disappears again. Evidently, an adaptation to these diets takes place.
KeywordsPeroxide Hydrate Urea Ketone NADPH
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