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Overview of Randomized Trials of Postoperative Adjuvant Radiotherapy in Breast Cancer

  • Conference paper
Cancer Clinical Trials

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 111))

Abstract

One of the first major randomized trials in cancer therapy was concerned with the value of postoperative adjuvant radiotherapy for breast cancer. Since then, a large number of trials have addressed this issue, but the impact of this treatment on long-term survival still remains clouded. This is due partly to the long natural history of breast cancer and partly to the changing approach to primary treatment, where a trend toward less surgery and more radiotherapy has taken place. The current interest in procedures aimed at breast conservation (Calle et al. 1978; Hell- man et al. 1980; Veronesi et al. 1981; Fisher et al. 1985 a) highlights this shift and emphasizes the need for a greater understanding of the role of radiotherapy in primary management.

We thank Dr. R. Edwards and Ms. I. Stratton for valuable computing assistance.

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Author information

Authors and Affiliations

  1. Imperial Cancer Research Fund, Lincoln’s Inn Fields, P.O.Box 123, London, WC2A 3PX, Great Britain

    J. Cuzick, H. J. Stewart, R. Peto, M. Baum, B. Fisher, H. Host, J. P. Lythgoe, G. Ribeiro, H. Scheurlen & A. Wallgren

Authors
  1. J. Cuzick
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  2. H. J. Stewart
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  3. R. Peto
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  4. M. Baum
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  5. B. Fisher
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  6. H. Host
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  7. J. P. Lythgoe
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  8. G. Ribeiro
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  9. H. Scheurlen
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  10. A. Wallgren
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Editor information

Editors and Affiliations

  1. Institut für Medizinische Biometrie und Informatik, Universität Heidelberg, Im Neuenheimer Feld 325, 6900, Heidelberg, Germany

    Hans Scheurlen

  2. Department of Probability and Statistics, University of Sheffield, Sheffield, S3 7RH, Great Britain

    Richard Kay

  3. King’s College, School of Medicine and Dentistry, CRC Clinical Trials Centre, Rayne Institute, 123 Coldharbour Lane, London, SE5 9NU, Great Britain

    Michael Baum

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© 1988 Springer-Verlag Berlin · Heidelberg

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Cuzick, J. et al. (1988). Overview of Randomized Trials of Postoperative Adjuvant Radiotherapy in Breast Cancer. In: Scheurlen, H., Kay, R., Baum, M. (eds) Cancer Clinical Trials. Recent Results in Cancer Research, vol 111. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83419-6_15

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  • DOI: https://doi.org/10.1007/978-3-642-83419-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83421-9

  • Online ISBN: 978-3-642-83419-6

  • eBook Packages: Springer Book Archive

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