Update 1988 pp 462-473 | Cite as

Pharmacology of Drugs in CPR

  • J. C. Mercier
  • J. F. Hartmann
  • F. Beaufils
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 5)


Cardiac arrest results in cessation of organ perfusion. Circulatory standstill leads to immediate cellular ischemia, anoxia and finally death. The brain is the most rapidly damaged organ, already after 4 to 6 minutes of cardiac arrest in human beings [1], maybe longer in very special circumstances such as in the child, or after drowning in iced water [2]. The myocardium is the second most vulnerable organ, which may tolerate 15 minute anoxia and recover. However, at least in children, the longer the cardiac arrest the less the chances to recover a spontaneously beating heart [3].


Cardiac Arrest Inferior Vena Cava Myocardial Blood Flow Cardiopulmonary Resuscitation Superior Vena Cava 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. C. Mercier
  • J. F. Hartmann
  • F. Beaufils

There are no affiliations available

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