Update 1988 pp 25-31 | Cite as

Oxygen Transport Following Major Trauma

  • J. D. Edwards
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 5)

Abstract

The concepts of oxygen delivery (DO2) are now well established and measurement of related variables are routinely made in critically ill patients [1], not least because measurement and manipulation of these variables has been shown to predict [2] and improve [3] outcome. Therefore the physiology of DO2 will not be reviewed in detail in this chapter but the terms used will be defined at the onset:
  • CaO2 = arterial O2 content (ml/dl)

  • Cv̄O2 = mixed venous O2 content (ml/dl)

  • SaO2 = arterial oxyhemoglobin saturation (%)

  • Sv̄O2 = mixed venous oxyhemoglobin saturation (%)

  • CI = cardiac index (1/min/m2)

Keywords

Expense Gelatin Dobutamine Shoe Cobo 

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References

  1. 1.
    Buran JM (1987) Oxygen consumption. In: Snyder JV, Pinsky MR (eds) Oxygen transport in the critically ill. Chicago, Year Book Medical Publishing Inc: pp. 16-21.Google Scholar
  2. 2.
    Bland RD, Shoemaker WC, Abraham E, Cobo JC (1985) Hemodynamic and oxygen transport patterns in surviving and non surviving postoperative patients. Crit Care Med 13:85–90.PubMedCrossRefGoogle Scholar
  3. 3.
    Shoemaker WC, Appel PL, Waxman K, et al (1982) Clinical trial of survivors cardiorespiratory patterns as therapeutic goals in critically ill postoperative patients. Crit Care Med 10:398–402.PubMedCrossRefGoogle Scholar
  4. 4.
    Snyder JV (1987) Patterns of hemodynamic response. In: Snyder JV, Pinsky MR (eds) Oxygen transport in the critically ill. Chicago, Year Book Medical Publishing Inc, pp 46–66.Google Scholar
  5. 5.
    Kandel G, Aberman A (1983) Mixed venous saturation. Its role in the assessment of the critically ill patient. Arch Intern Med 143:1400–1402.PubMedCrossRefGoogle Scholar
  6. 6.
    Kasnitz P, Druger GL, Yorra F, et al (1976) Mixed venous oxygen tension and hyperlactemia. Survival in severe cardiopulmonary disease. JAMA 236:570–574.PubMedCrossRefGoogle Scholar
  7. 7.
    Shibutani K, Komatsu T, Kubal K (1983) Critical level of oxygen delivery in anesthetized man. Crit Care Med 11:640–643.PubMedCrossRefGoogle Scholar
  8. 8.
    Danek SJ, Lynch JP, Weg JG, Dantzker DR (1980) The dependence on oxygen uptake on oxygen delivery in the Adult Respiratory Distress Syndrome. Am Rev Respir Dis 122:387–395.PubMedGoogle Scholar
  9. 9.
    Shoemaker WC (1987) Circulatory mechanisms of shock and their mediators. Crit Care Med 15:787–794.PubMedCrossRefGoogle Scholar
  10. 10.
    Champion HR, Sacco WJ (1986) Trauma severity scales. In: Maull KI, Cleveland HC, Strauch GO, Wolferth CC (eds) Advances in trauma, Vol 1, 1-20. Year Book Medical Publishers Inc Chicago.Google Scholar
  11. 11.
    Campion H, Sacco WJ, Hurst J (1983) Trauma severity scoring to predict mortality. World J Surg 7:4–11.CrossRefGoogle Scholar
  12. 12.
    Lowe DK, Gately HL, Goss JR, Frey CL, Peterson CG (1983) Patterns of death, complications, and error in the management of motor vehicle accident victims: implications for a regional system of trauma care. J Trauma 23:503.PubMedCrossRefGoogle Scholar
  13. 13.
    Boyd CR, Toison MA, Copes WS (1987) Evaluating trauma care: The TRISS method. J Trauma 27:370–378.PubMedCrossRefGoogle Scholar
  14. 14.
    Cuthbertson DP (1932) Observations on the disturbance of metabolism produced by injury to the limbs. Quart J Med 1:233–246.Google Scholar
  15. 15.
    Wilmore DW (1986) The wound as an organ. In: Little RA, Frayn KN (eds) The scientific basis for the care of the critically ill. Manchester University Press, pp 45-59.Google Scholar
  16. 16.
    Odling-Smee GW (1981) The metabolic response to injury. In: Odling-Smee GW, Crockard A (eds) Trauma care. London, Academic Press, pp 33–52.Google Scholar
  17. 17.
    Cuthbertson DP (1942) Post-shock metabolic response. Lancet 1:433–437.CrossRefGoogle Scholar
  18. 18.
    Shoemaker WC (1987) Relationship of oxygen transport patterns to the pathophysiology and therapy of shock states. Intensive Care Med 13:230–243.PubMedCrossRefGoogle Scholar
  19. 19.
    Stoner HB (1987) Interpretation of the metabolic effects of trauma and sepsis. J Clin Pathol 40:1108–1117.PubMedCrossRefGoogle Scholar
  20. 20.
    Cournand A, Riley RL, Bradley SE, et al (1943) Studies of the circulation in clinical shock. Surgery 13:964–995.Google Scholar
  21. 21.
    Shoemaker WC, Appel P, Czer LSC, et al (1980) Pathogenesis of respiratory failure (ARDS) after haemorrhage and trauma. Crit Care Med 8:504–512.PubMedCrossRefGoogle Scholar
  22. 22.
    Mayall RM, Edwards JD, Wilkins RG (1987) Importance of sampling site for measurement of mixed venous oxygen saturation. Crit Care Med 15:405 (Abstract).Google Scholar
  23. 23.
    Little RA (1985) Heat production after injury. Brit Med Bull 41:226–231.PubMedGoogle Scholar
  24. 24.
    Shatney CH (1985) Management of traumatic shock. In: Vincent JL (ed) Update in intensive care and emergency medicine. Springer, Berlin Heidelberg New York Tokyo, pp 247–253.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • J. D. Edwards

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