Abstract
The cardiovascular system is regulated by different control principles including local metabolic control at tissue levels and the overall neural and humoral regulation. It remains a major concern as to whether these complicated mechanisms remain intact or get affected by various diseases and/or anesthetic drugs in the perioperative period. The present paper briefly reviews the above mentioned control mechanisms and focuses on some clinically relevant disturbances of these regulatory circuits as result of diseases or pharmacological manipulations.
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References
Miletich DJ, Ivankovich AD, Albrecht RF, et al (1976) Absence of autoregulation of cerebral blood flow during halothane and enflurane anesthesia. Anesth Analg 55:100–109.
Fitch W, MacKenzie ET, Harper AM (1975) Effects of decreasing arterial blood pressure on cerebral blood flow in the baboon; influence of sympathetic nervous system. Circ Res 37:550–557.
Smith AL, Wollman H (1972) Cerebral blood flow and metabolism: effects of anesthetic drugs and techniques. Anesthesiology 36:378–395.
Shapiro HM (1974) Intracranial hypertension. Anesthesiology 43:445–471.
Marsh ML, Shapiro HM, Smith RW, et al (1979) Changes in neurologic status and intracranial pressure associated with sodium nitroprusside administration. Anesthesiology 51:336–338.
Buckley MJ, NcLaughlen JS, Fort L III, et al (1964) Effects of anesthetic agents on pulmonary vascular resistance during hypoxia. Surg Forum 15:183–184.
Lumb TD, Silvay G, Weinreich AI, et al (1979) A comparison of the effects of continuous ketamine infusion and halothane on oxygen during one lung anesthesia in dogs. Can Anaesth Soc J 26:394–401.
Bjertnaes LJ, Mundal R, Hauge A, et al (1980) Vascular resistance in atelectatic lungs: Effect of inhalation anesthetics. Acta Anaesthesiol Scand 24:109–118.
Mathers J, Benumof JL, Wahrenbrock EA (1977) General anesthetics and regional hypoxic pulmonary vasoconstriction. Anesthesiology 46:111–114.
Benumof JL (1979) Hypoxic pulmonary vasoconstriction and sodium nitroprusside infusion. Anesthesiology 50:481–483.
Bishop MJ, Cheney FW (1983) Minoxidil and nifedipine inhibit hypoxic pulmonary vasoconstriction. J Cardiovasc Pharmacol 5:184–189.
Tucker A, McMurtry IF, Grover RF, et al (1976) Attenuation of hypoxic pulmonary vasoconstriction by verapamil in intact dogs. Proc Soc Exp Biol Med 151:611–614.
Germann P, Aloy A, Zabloudil B, et al (1987) Treatment of subarachnoid hemorrhage with the calcium entry blocker nimodipine affects pulmonary gas exchange in patients requiring controlled mechanical ventilation. Anesthesiology 67:A115.
Lowenstein E, Foex P, Francis M, et al (1981) Regional ischemic ventricular dysfunction in myocardium supplied by a narrowed coronary artery with increasing halothane concentration in the dog. Anesthesiology 55:349–359.
Reiz S, Balfors E, Sorensen E, et al (1983) Isoflurane — a powerful coronary vasodilator in patients with coronary artery disease. Anesthesiology 59:91–97.
Buffington CW, Romson JL, Levine A, et al (1987) Isoflurane induces coronary steal in a canine model of chronic coronary occlusion. Anesthesiology 66:280–292.
Priebe HJ, Foëx P (1987) Isoflurane causes regional myocardial dysfunction in dogs with critical coronary artery stenoses. Anesthesiology 66:293–300.
Mayer N, Steinbereithner K, Zimpfer M (1986) Effects of halothane on the contractile performance of myocardium supplied by a chronically narrowed coronary artery in the dog. Anesthesiology 65:A59.
Zimpfer M, Mayer N, Steinbereithner K (1987) Dissimilar effects of isoflurane versus dipyridamole on myocardium supplied by a chronically narrowed coronary artery in the dog. Anesthesiology 67:A587.
Stoelting RK, (ed) (1987) Pharmacology and physiology in anesthetic practice. JB Lippincott, Philadelphia London Mexico City New York St. Louis Sao Paulo Sydney.
Kotrly KJ, Ebert TJ, Vucins E, et al (1984) Baroreceptor reflex control of heart rate during isoflurane anesthesia in humans. Anesthesiology 60:173–179.
Cox RH, Bagshaw RJ (1979) Influence of anesthesia on the response to carotid hypotension in dogs. Am J Physiol 237:H424–H432.
Zimpfer M, Beck A, Mayer N, et al (1983) Einfluß von Morphium auf die Kontrolle des kardiovaskulären Systems durch den Carotis-Sinus-Reflex und den Carotis-Chemoreflex. Anaesthesist 32:60–66.
Vatner SF, Boettcher DH, Heyndrickx GR, et al (1975) Reduced baroreflex sensitivity with volume loading in conscious dogs. Circ Res 37:236–242.
Eckberg DL, Drabinsky M, Braunwald E (1971) Defective cardiac parasympathetic control in patients with heart disease. N Engl J Med 285:877–883.
Zimpfer M, Sit SP, Vatner SF (1981) Effects of anesthesia on the carotid chemoreceptor reflex. Circ Res 48:400–406.
Beck A, Zimpfer M, Raberger G (1982) Inhibition of the carotid chemoreceptor reflex by enflurane in chronically instrumented dogs. Naunyn-Schmied. Arch Pharmacol 321:145–148.
Peters UH, Rieger H (Hrsg) (1976) Das Pickwick-Syndrom. Urban & Schwarzenberg, München.
Pathak CL (1966) The fallacy of the Bainbridge reflex. Am Heart J 72:577–581.
Vatner SF, Zimpfer M (1981) Bainbridge reflex in conscious unrestrained, and tranquilized baboons. Am J Physiol 240:H164–H167.
Boettcher DH, Zimpfer M, Vatner SF (1982) Phylogenesis of the Bainbridge reflex. Am J Physiol 242:R244–R246.
Zimpfer M, Kotai E, Mayer N, et al (1983) Einfluß von Morphin auf die Kreislaufkontrolle bei akuter progressiver Hämorrhagie. Anaesthesist 32:259–264.
Mayer N, Kotai E, Placheta P, et al (1985) Enflurane alters compensatory humoral and hemodynamic responses to hemorrhage. 7th Annual Meeting, Society of Cardiovascular Anesthesiologists, Phoenix, Arizona, p 111.
Boettcher DH, Vatner SF, Heyndrickx GR, et al (1978) Extent of utilization of the Frank Starling mechanism in conscious dogs. Am J Physiol 234:H338–H345.
Cohn LH, Klovekorn P, Moore FD, et al (1974) Intrinsic plasma volume deficits in patients with coronary artery disease. Arch Surg 108:57–60.
Zimpfer M, Mayer N, Gilly H, et al (1987) Cardiodynamics during rapid volume expansion and fuction of chronically ischemic myocardium under isoflurane: A study in chronically instrumented dogs. In: Peter K, Brown BR, Martin E, Norlander O (eds) Inhalation Anesthetics. New Aspects. Anaesthesiology and Intensive Care Medicine Vol 185. Springer, Berlin Heidelberg New York London Paris Tokyo, p 133–148.
Mayer N, Maurer E, Zimpfer M (1987) Untersuchungen zur Wertigkeit des Frank-Starling-Mechanismus im Verlauf akuter Volumsexpansion in Inhalationsanaesthesie. Anaesthesist 36 (Suppl):442, (V 30.1).
Zimpfer M, Blazek G (1983) Effects of prolonged inspiratory: expiratory ratio in critically ill patients — an echochardiographic evaluation. Crit Care Med Pvn11:243.
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© 1988 Springer-Verlag Berlin Heidelberg
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Mayer, N., Zimpfer, M. (1988). Cardiocirculatory Control Mechanisms in Health and Disease. In: Vincent, J.L. (eds) Update 1988. Update in Intensive Care and Emergency Medicine, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83392-2_1
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DOI: https://doi.org/10.1007/978-3-642-83392-2_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-18981-7
Online ISBN: 978-3-642-83392-2
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