Abstract
The genetic aspect of narcolepsy in man has long been considered, with the first report of a positive family history of narcolepsy made by Westphal (1877) even before the term “narcolepsy” was coined by Gelineau (1880). Since then a number of series have been published showing variable rates of probands with a positive family history of narcolepsy and suggesting either an autosomal dominant mode of inheritance with incomplete penetrance (Krabbe and Magnussen 1942; Daly and Yoss 1959; Baraitser and Parkes 1978) or a two-threshold multifactorial system (Nevsimalova-Bruhova and Roth 1972; Kessler 1976; Honda et al. 1983 a).
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Billiard, M. et al. (1988). HLA in Narcolepsy in France. In: Honda, Y., Juji, T. (eds) HLA in Narcolepsy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83387-8_6
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DOI: https://doi.org/10.1007/978-3-642-83387-8_6
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