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Positive HLA-Dw2 in Narcolepsy

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HLA in Narcolepsy

Abstract

Some authors reported that all the narcoleptic patients studied were positive for HLA-DR2 and DQw1 (Honda et al. 1984; Juji et al. 1984; Langdom et al. 1984; Billiard and Seignalet 1985). These findings prompted us to investigate HLA-D specificities of narcoleptics, because, in the Japanese population, HLA-D specificities that associate with HLA-DR2 have been reported to be HLA-Dw12 and less frequently Dw2, which is in contrast to the high correlation of HLA-DR2 and HLA-Dw2 (r value is approximately 0.9) in Caucasoid populations (Jaraquemada 1984).

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© 1988 Springer-Verlag Berlin Heidelberg

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Naohara, T., Honda, Y., Juji, T. (1988). Positive HLA-Dw2 in Narcolepsy. In: Honda, Y., Juji, T. (eds) HLA in Narcolepsy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83387-8_10

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  • DOI: https://doi.org/10.1007/978-3-642-83387-8_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83389-2

  • Online ISBN: 978-3-642-83387-8

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