Abstract
Four processes characterize a malignant neoplasm (Fig. 1).
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1
Autonomous local cell growth; the tumor cell becomes “correlation deaf”, owing to loss of inhibitory regulators.
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2
Tumor cell spread; penetration and metastases, the main indication of malignancy, caused by a large amount of enzyme activity, prostaglandins, etc.
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3
Pathologic products of metabolism that lead to the production of hormone-type communication.
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4
Host defence mechanisms that come into being mainly by immunologic processes (immune response). This means that a great variety of biochemical, immunologic and other reactions can be shown in every malignant process.
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References
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© 1988 Springer-Verlag Berlin Heidelberg
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Niebauer, G. (1988). Paraneoplasias of the Skin. In: Orfanos, C.E., Stadler, R., Gollnick, H. (eds) Dermatology in Five Continents. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83360-1_7
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DOI: https://doi.org/10.1007/978-3-642-83360-1_7
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