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Dermatology in Five Continents pp 47–53Cite as

Sun and Immunosurveillance

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Abstract

In the broadest sense, immunosurveillance refers to the ability of the immune system to detect and respond to foreign substances. These foreign substances, or antigens, can be microorganisms, foreign cells or tissues, complex molecules, such as proteins or carbohydrates, or even simple chemicals that bind to host cells and proteins. The body normally encounters all of these antigens on a continual basis, with one exception. Exposure to foreign tissues does not occur in nature, except perhaps during pregnancy. Thus, the immune system has an elaborate, highly efficient mechanism for ridding the body of something it seems not to encounter normally. Not believing that evolution would have permitted such folly, Thomas [1] and Burnet [2] independently proposed in the 1950s that allograft rejection evolved as a means of eliminating cancer cells that arose within the body.

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Author information

Authors and Affiliations

  1. Department of Immunology, M. D. Anderson Hospital and Tumor Institute, University of Texas System Cancer Center, Houston, Texas, USA

    M. L. Kripke

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  1. M. L. Kripke
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Editors and Affiliations

  1. Universitäts-Hautklinik und Poliklinik, Klinikum Steglitz der Freien Universität, Hindenburgdamm 30, D-1000, Berlin 45, Federal Republic of Germany

    Constantin E. Orfanos (CMD — Scientific Secretariat), Rudolf Stadler (CMD — Scientific Secretariat) & Harald Gollnick (CMD — Scientific Secretariat) (CMD — Scientific Secretariat),  (CMD — Scientific Secretariat) &  (CMD — Scientific Secretariat)

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© 1988 Springer-Verlag Berlin Heidelberg

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Kripke, M.L. (1988). Sun and Immunosurveillance. In: Orfanos, C.E., Stadler, R., Gollnick, H. (eds) Dermatology in Five Continents. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83360-1_5

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  • DOI: https://doi.org/10.1007/978-3-642-83360-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83362-5

  • Online ISBN: 978-3-642-83360-1

  • eBook Packages: Springer Book Archive

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