Melanoma: Clinical and Therapeutic Aspects
The present-day concept of carcinogenesis includes three stages of development: first, the initiation stage in which a normal cell is affected by a carcinogenic initiator causing genetic damage but leaving the cell phenotypically unaltered: second, a promotion stage in which the genetic damage results in the growth of a visible tumor is essentially benign but has an increased probability for malignant transformation: and, third, the stage of progression during which the tumor infiltrates adjacent tissues and metastasizes.
KeywordsToxicity Oncol Interferon Cyclophosphamide Indomethacin
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