Skip to main content
SpringerLink
Log in
Book cover

Dermatology in Five Continents pp 346–354Cite as

Melanoma: Clinical and Therapeutic Aspects

  • Conference paper

  • 144 Accesses

Abstract

The present-day concept of carcinogenesis includes three stages of development: first, the initiation stage in which a normal cell is affected by a carcinogenic initiator causing genetic damage but leaving the cell phenotypically unaltered: second, a promotion stage in which the genetic damage results in the growth of a visible tumor is essentially benign but has an increased probability for malignant transformation: and, third, the stage of progression during which the tumor infiltrates adjacent tissues and metastasizes.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ackerman AB (1985) Malignant melanoma in situ: the flat, curable stage of malignant melanoma. Pathology 17:298–300.

    Article  PubMed  CAS  Google Scholar 

  2. Clark WH Jr, Ainsworth AM, Bernardino EA et al (1985) The developmental biology of primary human malignant melanoma. Semin Oncol 2:83.

    Google Scholar 

  3. Clark WH Jr, Elder DE, Guerry D IV, et al. (1984) A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 15:1147.

    Article  PubMed  Google Scholar 

  4. Elder DE, Guerry D IV, Epstein MN et al. (1984) Invasive malignant melanomas lacking competence for metastasis. Am J Dermatopathol 6 (Suppl 1):55.

    PubMed  Google Scholar 

  5. Kleeberg UR, Voigt H (1986) Experimentelle Therapieansätze. In: Malignes Melanom. Springer, Berlin Heidelberg New York, pp 121–127.

    Google Scholar 

  6. Voigt H, Kleeberg UR (1986) Systemische Chemotherapie maligner Melanome. In: Kleeberg UR, Voigt H (eds) Malignes Melanom, Springer, Berlin Heidelberg New York, pp 235–298.

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Dermatology, University of Münster, Münster, FR Germany

    E. Macher (Chairman)

  2. Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA

    T. Fitzpatrick (Co-Chairman) & T. B. Fitzpatrick

  3. Department of Dermatology, University of Lund, Lasarette, Sweden

    H. Rorsman (Co-Chairman)

  4. Department of Dermatology I, University of Vienna, Vienna, Austria

    K. Wolff

  5. Division of Dermatology, The Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

    A. R. Rhodes

  6. Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

    M. C. Mihm

  7. Department of Dermatology, New York University, New York, USA

    A. B. Ackerman

  8. Department of Dermatology, University of Philadelphia, Philadelphia, USA

    W. H. Clark Jr.

  9. Department of Surgical Oncology, National Cancer Institute, Milan, Italy

    N. Cascinelli

  10. Hamburg, FR Germany

    U. R. Kleeberg

  11. Department of Pathology and Surgery, University of California, Los Angeles, California, USA

    A. J. Cochran

  12. Amsterdam, The Netherlands

    T. Rümke

Authors
  1. E. Macher
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. Fitzpatrick
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Rorsman
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. B. Fitzpatrick
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. Wolff
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. R. Rhodes
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. M. C. Mihm
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. A. B. Ackerman
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. W. H. Clark Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. N. Cascinelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. U. R. Kleeberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. A. J. Cochran
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. T. Rümke
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Universitäts-Hautklinik und Poliklinik, Klinikum Steglitz der Freien Universität, Hindenburgdamm 30, D-1000, Berlin 45, Federal Republic of Germany

    Constantin E. Orfanos (CMD — Scientific Secretariat), Rudolf Stadler (CMD — Scientific Secretariat) & Harald Gollnick (CMD — Scientific Secretariat) (CMD — Scientific Secretariat),  (CMD — Scientific Secretariat) &  (CMD — Scientific Secretariat)

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Macher, E. et al. (1988). Melanoma: Clinical and Therapeutic Aspects. In: Orfanos, C.E., Stadler, R., Gollnick, H. (eds) Dermatology in Five Continents. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83360-1_47

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83360-1_47

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83362-5

  • Online ISBN: 978-3-642-83360-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation