Abstract
Conservative surgery and radiation therapy (CS + RT) has been shown to be an effective method of local treatment of early breast cancer, with survival rates equivalent to those following mastectomy. In view of this, more attention is now being focused on risk factors of local recurrence following CS + RT in an attempt to refine selection criteria and treatment techniques.
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Alpert S, Ghossein NA, Stacey P, Migliorelli FA, Efron G, Krishnaswamy V (1978) Primary management of operable breast cancer by minimal surgery and radiotherapy. Cancer 42: 2054–2058
Amalric R, Santamaria F, Robert F, Seigle J, Altshuler C, Pietra JC, Amalric F, Kurtz JM, Spitalier JM, Brandone H, Ayme Y, Pollet JF, Bressac C, Fondarai J (1983) Conservative therapy of operable breast cancer-results at five, ten and fifteen years in 2216 consecutive cases. In: Harris JR, Hellman S, Silen W (eds) Conservative management of breast cancer. Lippincott, Philadelphia, pp 30–34
Bataini JP, Picco C, Martin M, Calle R (1978) Relation between time-dose and local control of operable breast cancer treated by tumorectomy and radiotherapy or by radical radiotherapy alone. Cancer 42: 2059–2065
Bedwinek J, Perez CA, Kramer S, Brady L, Goodman R, Grundy G (1980) Irradiation as the primary management of stage I and II adenocarcinoma of the breast. Cancer Clin Trials 3: 11–18
Calle R, Vilcoq JR, Zafrani B, Vielh P, Fourquet A (1986) Local control and survival of breast cancer treated by limited surgery followed by irradiation. Int J Radiat Oncol Biol Phys 12: 873–878
Clarke DH, Le MG, Sarrazin D, Lancombe M-J, Fontaine F, Travagli J-P, Françoise M-L, Contesso G, Arriagada R (1985) Analysis of local-regional relapse in patients with early breast cancers treated by excision and radiotherapy. Experience of the Institut Gustave- Roussy. Int J Radiat Oncol Biol Phys 11: 137–145
Connolly JL, Leopold KA, Recht A, Schnitt SJ, Rose MA, Silver B, Harris JR (1987) Results of conservative surgery and radiation therapy for multiple synchronous cancers of one breast. Int J Radiat Oncol Biol Phys 13: 160 (Abstract)
Delouche G, Bachelot F, Premont M, Kurtz JM (1987) Conservation treatment of early breast cancer: Long term results and complications. Int J Radiat Oncol Biol Phys 13: 29–34
Fisher B, Wolmark N, Bauer M, Redmond C, Gebhardt M (1981) The accuracy of clinical nodal staging and of limited axillary dissection as a determinant of histological nodal status in carcinoma of the breast. Surg Gynecol Obstet 152: 765–772
Fisher B, Bauer M, Margolese R, Poisson R, Pilch Y, Redmond C, Fisher E, Wolmark N, Deutsch M, Montague E, Saffer E, Wickerman L, Lerner H, Glass A, Shibata H, Deckers P, Ketchman A, Oishi R, Russell I (1985) Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med 312: 665–673
Harris JR, Botnick LE, Bloomer WD, Chaffey JT, Hellman S (1981) Primary radiation therapy for early breast cancer: the experience at the Joint Center for Radiation Therapy. Int J Radiat Oncol Biol Phys 7: 1549–1552
Hunig R, Walther E, Harder F, Almendral AC, Roth J, Torhorst J (1983) The Basel lumpectomy protocol: five-year experience with a prospective study for conservative treatment of breast cancer. In: Harris JR, Hellman S, Silen W (eds) Conservative management of breast cancer. Lippincott, Philadelphia, pp 23–25
Kurtz JM, Spitalier JM, Amalric R (1983) Late breast recurrence after lumpectomy and irradiation. Int J Radiat Oncol Biol Phys 7: 1191–1194
Kurtz JM, Brandone H, Ayme Y, Spitalier JM, Amalric R (1987) Mammary recurrences in women younger than forty. Int J Radiat Oncol Biol Phys 14: 183 (Abstract)
Luini A, Sacchini V, Galimberti V, Farante G, Del Vecchio M, Tana S, Volterrani F, Veronesi U (1987) Conservative treatment of early breast carcinoma: report on 83 T2 patients treated with QU.A.RT. Breast Cancer Res Treat 10: 106 (Abstract)
Muscolino G, Luini A, Bedini AV, Beretta E, Sacchini V (1987) Impact of young age on local recurrence risk in patients with early breast cancer undergone Qu. A. RT. Breast Cancer Res Treat 10: 105 (Abstract)
Nobler MP, Venet L (1985) Prognostic factors in patients undergoing curative irradiation for breast cancer. Int J Radiat Oncol Biol Phys 11: 1323–1331
Osborne MP, Ormiston N, Harmer CL, McKinna J A, Baker J, Greening WP (1984) Breast conservation in the treatment of early breast cancer. Cancer 53: 349–355
Recht A, Silver B, Schnitt S, Connolly J, Hellman S, Harris JR (1985) Breast relapse following primary radiation therapy for early breast cancer. I. Classification, frequency and salvage. Int J Radiat Oncol Biol Phys 11: 1271–1276
Schnitt SJ, Connolly JL, Harris JR, Hellman S, Cohen RB (1984) Pathologic predictors of early local recurrence in Stage I and II breast cancer treated by primary radiation therapy. Cancer 53: 1049–1057
Schnitt SJ, Connolly JL, Khettry U, Mazoujian G, Brenner M, Silver B, Recht A, Beadle G, Harris JR (1987) Pathologic findings on re-excision of the primary site in breast cancer patients considered for treatment by primary radiation therapy. Cancer 59: 675–681
Solin LJ, Fowble B, Martz KL, Pajak TF, Goodman RL (1986) Does residual tumor adversely impact on the outcome of patients undergoing definitive irradiation for early stage breast cancer. Int J Radiat Oncol Biol Phys 12: 91–92 (Abstract)
Solin LJ, Fowble B, Schultz DJ, Goodman RL (1987) Age as a prognostic factor for patients treated with definitive irradiation for early stage breast cancer. Int J Radiat Oncol Biol Phys 14: 184 (Abstract)
Svensson GK, Bjarngard BE, Larson RD, Levene MB (1980) A modified three-field technique for breast treatment. Int J Radiat Oncol Biol Phys 6: 689–694
Valagussa P, Bonadonna G, Veronesi U (1978) Patterns of relapse and survival following radical mastectomy: analysis of 716 consecutive patients. Cancer 41: 1170–1178
van Limbergen E, van der Bogaert W, van der Schueren E, Rijnders A (1987) Tumor excision and radiotherapy as primary treatment of breast cancer. Analysis of patient and treatment parameters and local control. Radiother Oncol 8: 1–9
Veronesi U, Zucali R, Luini A (1986) Local control and survival in early breast cancer: the Milan trial (1986) Int J Radiat Oncol Biol Phys 12: 717–720
Vilcoq JR, Calle R, Stacey P, Ghossein NA (1981) The outcome of treatment by tumorectomy and radiotherapy of patients with operable breast cancer. Int J Radiat Oncol Biol Phys 7: 1327–1332
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© 1989 Springer-Verlag Berlin · Heidelberg
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Boyages, J. et al. (1989). Factors Associated with Local Recurrence as a First Site of Failure Following the Conservative Treatment of Early Breast Cancer. In: Senn, HJ., Goldhirsch, A., Gelber, R.D., Osterwalder, B. (eds) Adjuvant Therapy of Primary Breast Cancer. Recent Results in Cancer Research, vol 115. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83337-3_13
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DOI: https://doi.org/10.1007/978-3-642-83337-3_13
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