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Protein Antigens of Campylobacter pylori: The Problem of Species Specificity

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Campylobacter pylori

Abstract

Since Campylobacter pylori (C. pylori) was first isolated and identified from gastric biopsies by Marshall [6], data have accumulated which indicate a strong association of C. pylori with gastritis and peptic ulcer disease [14]. Despite this fact the natural course of infection, the pathomechanisms, and the occurrence in the total population remain largely unclear.

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References

  1. Goodwin CS, Blincow E, Peterson G, Sanderson C, Cheng W, Marshall B, Warren JR, Mc–Culloch R (1987) Enzyme–linked immunosorbent assay for Campylobacter pyloridis: Correlation with presence of C. pyloridis in the gastric mucosa. J Inf Dis 155:488–494

    Article  CAS  Google Scholar 

  2. Jones DM, Lessells AM, Eldridge J (1984) Campylobacter–like organisms on the gastric mucosa: Culture, histological and serological studies. J Clin Pathol 37:1002–1006

    Article  PubMed  CAS  Google Scholar 

  3. Jones DM, Eldridge J, Fox AJ, Sethi P, Whorwell PJ (1986) Antibody to the gastric campylobacter–like organism (“Campylobacter pyloridis”). Clinical correlations and distribution in the normal population. J Med Microbiol 22:57–62

    Article  PubMed  CAS  Google Scholar 

  4. Kaldor J, Tee W, McCarthy P, Watson J, Dwyer B (1985) Immune response to Campylobacter pyloridis in patients with peptic ulceration. Lancet 1:921

    Article  PubMed  CAS  Google Scholar 

  5. Lee A, Logan SM, Trust TJ (1987) Demonstration of a flagellar antigen shared by a diverse group of spiral–shaped bacteria that colonize intestinal mucus. Infect Immun 55:828–831

    PubMed  CAS  Google Scholar 

  6. Marshall B (1983) Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1:1273–1275

    Google Scholar 

  7. Marshall BJ, McGeckie DB, Francis GJ, Utley PJ (1984) Pyloric Campylobacter serology. Lancet 2:281

    Article  PubMed  CAS  Google Scholar 

  8. McNulty CAM, Crump B, Gearty J, Lister DM, Davies M, Donovan IA, Melikian V, Wise R (1985) The distribution of and serological response to Campylobacter pyloridis in the stomach and duodenum. In: Campylobacter III: Proceedings of the Third International Workshop on Campylobacter infections. Public Health Laboratory Service, London, pp 174–175

    Google Scholar 

  9. Megraud F, Bonnet F, Gamier M, Lamouliatte H (1985) Characterization of “Campylobacter pyloridis” by culture, enzymatic profile, and protein content. J Clin Microbiol 22:1007–1010

    PubMed  CAS  Google Scholar 

  10. Newell DG (1987) Identification of the outer membrane proteins of Campylobacter pyloridis and antigenic cross–reactivity between C. pyloris and C. jejuni. J Gen Microbiol 133:163–170

    PubMed  CAS  Google Scholar 

  11. Pearson AD, Bamforth J, Booth L, Holdstock G, Ireland A, Walker C, Hawtin P, Millward–Sadler H (1984) Polyacrylamide gel electrophoresis of spiral bacteria from the gastric antrum. Lancet 1:1349–1350

    Article  PubMed  CAS  Google Scholar 

  12. Perez–Perez GI, Blaser MJ (1987) Conservation and diversity of Campylobacter pyloridis major antigens. Infect Immun 55:1256–1263

    PubMed  CAS  Google Scholar 

  13. Rathbone BJ, Wyatt J, Worsley BW, Trejdosiewicz LK, Heatley RV, Losowsky MS (1985) Immune response to Campylobacter pyloridis. Lancet 1:1217

    Article  PubMed  CAS  Google Scholar 

  14. Rathbone BJ, Wyatt JI, Heatly RV (1986) Campylobacter pyloridis – a new factor in peptic ulcer disease? Gut 27:635–641

    Article  PubMed  CAS  Google Scholar 

  15. Steraberger LA, Hardy PH, Cuculi JJ, Meyer HC (1970) The unlabeled antibody enzyme methods of immunohistochemistry. J Histochem Cytochem 18:315–333

    Article  Google Scholar 

  16. Towbin H, Staehlin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc Natl Acad Sci USA 76:4350–4354

    Article  CAS  Google Scholar 

  17. Wulffen v H, Heesemann J, Bützow GH, Löning T, Laufs R (1986) Detection of Campylobacter pyloridis in patients with antrum gastritis and peptic ulcers by culture, complement fixation test and immunoblot. J Clin Microbiol 24:716–720

    Google Scholar 

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Authors
  1. M. Kist
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  2. I. Apel
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  3. E. Jacobs
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Editor information

Editors and Affiliations

  1. Medizinische Klinik II, Krankenanstalten der Stadt Remscheid, Akademisches Lehrkrankenhaus der Universität Bonn, Hans-Potyka-Straße 28, 5630, Remscheid 11, Germany

    H. Menge

  2. Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, 1000, Berlin 45, Germany

    M. Gregor

  3. Department of Gastroentero-Hepatology, Academisch Medisch Centrum , Academisch Ziekenhuis bij de Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

    G. N. J. Tytgat

  4. Division of Gastroenterology, Department of Internal Medicine, University of Virginia, Box 145, Charlottesville, VA, 22908, USA

    B. J. Marshall

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© 1988 Springer-Verlag Berlin Heidelberg

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Kist, M., Apel, I., Jacobs, E. (1988). Protein Antigens of Campylobacter pylori: The Problem of Species Specificity. In: Menge, H., Gregor, M., Tytgat, G.N.J., Marshall, B.J. (eds) Campylobacter pylori. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83322-9_3

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  • DOI: https://doi.org/10.1007/978-3-642-83322-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83324-3

  • Online ISBN: 978-3-642-83322-9

  • eBook Packages: Springer Book Archive

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