Current Theories on Pathogenesis of Peptic Ulcer Disease

  • W. Roesch
Conference paper


While in the nineteenth century duodenal ulcer was extremely rare and gastric ulcer was essentially a disease of young women, epidemiology changed during the first half of this century, with male predominance and duodenal ulcers leading by about 4:1 (Langman, 1979). Recently there has been a constant decrease, at least in hospital admissions, for peptic ulcer disease, especially in duodenal ulcers, while the complication rates remain constant or even show a considerable increase in older patients, with hemorrhage and perforation, most probably due to consumption of nonsteroidal anti-inflammatory drugs (Wait et al., 1985).


Peptic Ulcer Duodenal Ulcer Gastric Ulcer Peptic Ulcer Disease Ulcer Healing 
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© Springer-Verlag Berlin Heidelberg 1988

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  • W. Roesch

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