Predictive Assays for the Therapy of Rectal Carcinoma

  • C. Streffer
  • D. van Beuningen
  • M.-L. Mlynek
  • E. Gross
  • F.-W. Eigler
Conference paper
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 110)


The decision about the therapeutic treatment of an individual tumor is made on the basis of the localization and the clinical as well as the histopathological staging. However, very different responses to such a treatment are observed for tumors with the same clinical and histopathological stage. From this general clinical expe rience it can be concluded that these tumors differ very much in their individual biological characteristics, which are relevant for the therapeutic response, and more biological data are needed in order to improve the selection of the appropriate therapeutic modality on an individual basis as well as to obtain better prognostic factors [1, 2].


Rectal Carcinoma Radiation Response Micronucleus Test Vascularization Index Histopathological Stage 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • C. Streffer
    • 1
  • D. van Beuningen
    • 1
  • M.-L. Mlynek
    • 2
  • E. Gross
    • 3
  • F.-W. Eigler
    • 3
  1. 1.Institut für Medizinische StrahlenbiologieUniversitätsklinikum EssenEssen 1Germany
  2. 2.Institut für PathologieUniversitätsklinikum EssenGermany
  3. 3.Klinik für Allgemeine ChirurgieUniversitätsklinikum EssenGermany

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