Abstract
There are two main problems in the treatment of anal cancer. Obviously, it is important to achieve local tumor control and a high survival rate, and, if possible, treatment should be conservative to retain normal anal function. This cancer should not be treated by surgery only or by percutaneous radiotherapy only for the following reasons:
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1
Anal carcinomas are accessible to interstitial radiotherapy.
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2
The tumor and lymph node secondaries are highyl radiosensitive but regression is slow.
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3
There is a high frequency of sequelae (radionecrosis) when the perineal region receives high doses of radiation.
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4
Permanent colostomy is necessary for a majority of surgically treated patients.
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© 1988 Springer-Verlag Berlin Heidelberg
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Dobrowsky, W., Dobrowsky, E. (1988). Combined Modality Treatment of Anal Carcinoma. In: Schlag, P., Hohenberger, P., Metzger, U. (eds) Combined Modality Therapy of Gastrointestinal Tract Cancer. Recent Results in Cancer Research, vol 110. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83293-2_21
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DOI: https://doi.org/10.1007/978-3-642-83293-2_21
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