Combined Modality Treatment of Anal Carcinoma

  • W. Dobrowsky
  • E. Dobrowsky
Conference paper
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 110)


There are two main problems in the treatment of anal cancer. Obviously, it is important to achieve local tumor control and a high survival rate, and, if possible, treatment should be conservative to retain normal anal function. This cancer should not be treated by surgery only or by percutaneous radiotherapy only for the following reasons:
  1. 1

    Anal carcinomas are accessible to interstitial radiotherapy.

  2. 2

    The tumor and lymph node secondaries are highyl radiosensitive but regression is slow.

  3. 3

    There is a high frequency of sequelae (radionecrosis) when the perineal region receives high doses of radiation.

  4. 4

    Permanent colostomy is necessary for a majority of surgically treated patients.



Anal Canal Anal Cancer Local Tumor Control Epidermoid Carcinoma Combine Modality Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • W. Dobrowsky
    • 1
  • E. Dobrowsky
    • 1
  1. 1.Klinik für Radiotherapie und RadiobiologieUniversität WienWienAustria

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