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Preoperative Radiotherapy and Radical Surgery as Combined Treatment in Rectal Cancer

  • A. Gerard
  • J. L. Berrod
  • F. Pene
  • J. Loygue
  • A. Laugier
  • R. Bruckner
  • G. Camelot
  • J. P. Arnaud
  • U. Metzger
  • M. Buyse
  • O. Dalesio
  • N. Duez
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 110)

Abstract

In 1976, the Gastrointestinal Group of the EORTC activated a clinical trial on rectal cancer with the aim of studying the efficacy of high-dose preoperative irradiation therapy (34.5 Gy) as an adjuvant before radical surgery. This was a multicentric prospective phase-III clinical trial.

Keywords

Rectal Cancer Radical Surgery Preoperative Irradiation Anal Margin Irradiation Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Boulis-Wassif S, Gerard A (1978) EORTC clinical trial with rectal cancer (preliminary report). In: Gerard A (ed) Gastrointestinal tumors. A clinical and experimental approach. Pergamon, OxfordGoogle Scholar
  2. 2.
    Boulis-Wassif S, Gerard A, Loygue J, Camelot D, Buyse M, Duez N (1984) Final results of a randomized trial on the treatment of rectal cancer with preoperative radiotherapy alone or in combination with 5-fluorouracil, followed by radical surgery. Trial of the European Organization on Research and Treatment of Cancer, Gastrointestinal Tract Cancer Cooperative Group. Cancer 53: 1811–1818Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • A. Gerard
    • 1
  • J. L. Berrod
    • 1
  • F. Pene
    • 1
  • J. Loygue
    • 1
  • A. Laugier
    • 1
  • R. Bruckner
    • 1
  • G. Camelot
    • 1
  • J. P. Arnaud
    • 1
  • U. Metzger
    • 1
  • M. Buyse
    • 1
  • O. Dalesio
    • 1
  • N. Duez
    • 1
  1. 1.Institut Jules BordetBrusselsBelgium

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