Pathophysiology of Tumors in Hyperthermia

  • P. Vaupel
  • F. Kallinowski
  • M. Kluge
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 107)


The response of tumor cells to hyperthermia is critically influenced by a number of pathophysiological factors both in vitro and in vivo. The most relevant factors in this context are tumor blood flow, tissue oxygenation, the energy status, and the pH distribution, which in turn define the cellular microenvironment.


Tissue Temperature Blood Flow Change Tumor Blood Flow Thermal Dose Human Breast Cancer Xenograft 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin · Heidelberg 1988

Authors and Affiliations

  • P. Vaupel
    • 1
  • F. Kallinowski
    • 1
  • M. Kluge
    • 1
  1. 1.Abteilung für Angewandte PhysiologieUniversität MainzMainzGermany

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