Abstract
The clinical use of an annular phased array system of electromagnetic wave applicators for regional heating of deep-seated tumors has been previously reported (Sapozink et al. 1984,1986; Emami et al. 1984; Gibbs et al. 1984; Howard et al. 1986). In these studies the patients received regional hyperthermia combined with radiotherapy. The rationale for this combined treatment modality is based on biological data in vitro and in vivo indicating a synergistic interaction between heat and radiation (Dewey 1984). In clinical studies on superficial human tumors, combined hyperthermia and radiotherapy has been shown to be superior to either modality alone in achieving complete responses (Overgaard 1985).
This work was supported by grants M12/85 Wil, M41/85 Wi2, and M10/86 Wi3 from the Deutsche Krebshilfe. Part of this work was presented at the 8th International Congress of Radiation Research, Edinburgh, United Kingdom, July 1987.
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© 1988 Springer-Verlag Berlin · Heidelberg
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Issels, R.D., Wadepohl, M., Tiling, K., Müller, M., Sauer, H., Wilmanns, W. (1988). Regional Hyperthermia Combined with Systemic Chemotherapy in Advanced Abdominal and Pelvic Tumors: First Results of a Pilot Study Employing an Annular Phased Array Applicator. In: Issels, R.D., Wilmanns, W. (eds) Application of Hyperthermia in the Treatment of Cancer. Recent Results in Cancer Research, vol 107. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83260-4_35
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DOI: https://doi.org/10.1007/978-3-642-83260-4_35
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