Abstract
Immunological disorders of the nervous system are strongly influenced by the blood-brain barrier (BBB) and the blood-nerve barrier (BNB). Recently, the BNB was demonstrated, by means of an experimental tracer study, to differ from the BBB in having greater permeability to IgG (1). Since the BNB is known to be impaired in inflammatory neuropathies, it was the aim of this study to determine to what extent the permeability of the BNB is altered for IgG and other serum proteins during Wallerian degeneration and subsequent regeneration.
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Seitz RJ, Heininger K, Schwendemann G, Toyka KV, Wechsler W (1985) The mouse blood-brain barrier and blood-nerve barrier for IgG: A tracer study by use of the avidin-biotin complex. Acta Neuropathol (Berl) 68:15–21
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© 1987 Springer-Verlag Berlin Heidelberg
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Seitz, R.J., Reiners, K., Heininger, K., Hartung, H.P., Toyka, K.V. (1987). Changes of the Blood-Nerve Barrier During Nerve Regeneration in the Mouse. In: Poeck, K., Hacke, W., Schneider, R. (eds) Neuroimmunologie Spinale Krankheiten Neuropsychologie Metabolische Enzephalopathien Neurologische Notfälle Interventionelle Neuroradiologie. Verhandlungen der Deutschen Gesellschaft für Neurologie, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83201-7_14
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DOI: https://doi.org/10.1007/978-3-642-83201-7_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-18254-2
Online ISBN: 978-3-642-83201-7
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