Disturbances in Microcirculatory Regulation in Septic Shock

  • D. H. Lewis
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 4)


The present chapter will deal with a number of aspects of regulation of the microcirculation caused by disturbances in central circulatory regulatory mechanisms that affect directly the way in which the microcirculation carries out its various functions. The details of the microcirculatory alterations will be covered in K. Messmer’s chapter. Specifically, we will consider briefly the effects of the activity of the sympathetic nervous system on the microcirculation (for a more detailed analysis, see [1]) and the heart as well as the significance of changes in polymorphonuclear leukocytes and endothelial cells.


Septic Shock Sympathetic Nervous System Polymorphonuclear Leukocyte Muscle Blood Flow Circ Shock 
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© Springer-Verlag Berlin Heidelberg 1987

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  • D. H. Lewis

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