Abstract
Nutritional disturbances are extremely common in patients requiring intensive care and such disturbances have far reaching consequences. The critically ill develop a marked stress response to trauma with disturbances of carbohydrate, fat and protein metabolism. Oxygen consumption is increased, fluid overload common and susceptibility to sepsis is very high. The effects of malnutrition are legion. Acute weight loss in excess of 20% is associated with a postoperative mortality of 33%, compared with 3.5% in those who had lost less weight. Malnutrition is generally held, however, to lead to progressive weakness, although the efficacy of perioperative parenteral nutrition in reducing mortality and morbidity has been questioned by Biebuyck [1]. The ability to respond to infection is attributable in part to a group of proteins, leucocyte endogenous mediators, which are reduced in malnutrition and restored by increasing protein intake.
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© 1987 Springer-Verlag Berlin Heidelberg
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Willatts, S.M. (1987). Parenteral Nutrition: When and How?. In: Vincent, J.L. (eds) Update 1987. Update in Intensive Care and Emergency Medicine, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83042-6_5
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DOI: https://doi.org/10.1007/978-3-642-83042-6_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-17576-6
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