Structural Transformations in DNA

  • S. M. Lindsay
Conference paper
Part of the Springer Series in Solid-State Sciences book series (SSSOL, volume 69)

Abstract

DNA undergoes displacive transitions between the A, B and z forms, and order-disorder transitions such as the strand separation. The displacive transitions may be controlled by the highly charged phosphate backbone of the polymer interacting via the surrounding electrolyte. Interactions between neighboring molecules dominate the A to B transition since A-DNA appears only in concentrated (aggregated) solutions or in fibers, and the degree to which adjacent molecules are aligned parallel controls the transition rate. Modes of GHz. frequencies are probably involved in the dynamical pathways of these transitions and this is a frequency region in which the dynamics of the surrounding hydration shell needs to be considered explicitly. This is because the water close to the double helix (primary hydration) undergoes a viscoelastic transition at about 4 GHz. while the more remote water (secondary hydration) undergoes this transition at about 80 GHz. Melting can be brought about by an increase in the phonon population in the small bandwidth occupied by modes which contribute stretch amplitude to the bridging hydrogen bonds.

Keywords

Hydration Soliton Adenine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • S. M. Lindsay
    • 1
  1. 1.Physics DepartmentArizona State UniversityTempeUSA

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