Skip to main content

Hyperlipoproteinemia in the Pathogenesis of Acute Pancreatitis

  • Chapter
Acute Pancreatitis

Abstract

For 120 years it has been well known that attacks of acute pancreatitis are occasionally associated with marked hyperlipoproteinemia [1]. Pancreatitis in such cases is usually of the relapsing type. The serum is of milky turbidity and the concentration of triglycerides is extremely high, usually more than 30 mmol/l. Attacks of this type of pancreatitis appear characteristically in early age, often in early childhood. This is in contrast to the more common type of relapsing pancreatitis of other origin, which generally affects the middle-aged and seldomly occurs in early life.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Speck L (1865) Fall von Lipämia. Archiv des Vereins für wissenschaftliche Heilkunde 1:232

    Google Scholar 

  2. Frederickson DS, Lees RS (1965) A system for phenotyping hyperlipoproteinemia. Circulation 31:321

    Google Scholar 

  3. Havel RJ, Gordon RS (1960) Idiopathic hyperlipemia: metabolic studies in an affected family. J Clin Invest 39:1777

    Article  PubMed  CAS  Google Scholar 

  4. Krauss RM, Levy AG (1977) Subclinical chronic pancreatitis in type I hyperlipoproteinemia. Am J Med 62:144

    Article  PubMed  CAS  Google Scholar 

  5. Löffler A, Löffler-Bock AH, Friedrichs U (1976) Hyperlipoproteinamie und Pankreatitis. Leber Magen Darm 6:249–252

    PubMed  Google Scholar 

  6. Herfort K, Sobra J, Fric P, Heyrovsky A (1971) Familial hyperlipoproteinemia and exocrine pancreas. Scand J Gastroenterol 6:193–143

    Article  Google Scholar 

  7. Frederickson DS, Levy RJ (1972) In: Stanbury JB, Wyngaarden JB, Frederickson DS (eds) The metabolic basis of inherited diseases, 3rd edn. McGraw Hill, New York, p 545

    Google Scholar 

  8. de Gennes JL, Thomopoulos P, Truffet J (1974) Les pancréatites des hyperlipidémies idio-pathiques. Ann Med Interne (Paris) 125:333

    Google Scholar 

  9. Coffey RJ (1952) Unusual features of acute pancreatic disease. Ann Surg 135:715

    Article  PubMed  CAS  Google Scholar 

  10. Bouchon JP (1970) Pankreatitis und Hyperlipidämie. In: Wyss F, Hartmann G (eds) Die Hyperlipidämie in Klinik und Praxis. Huber, Bern

    Google Scholar 

  11. Greenberger NJ (1973) Pancreatitis and hyperlipemia. N Engl J Med 289:586

    Article  PubMed  CAS  Google Scholar 

  12. Farmer RG, Winkelman EJ, Brown HB, Lewis LA (1973) Hyperlipoproteinemia and pancreatitis. Am J Med 54:161

    Article  PubMed  CAS  Google Scholar 

  13. Wang C, Adlersberg D, Feldman EB (1959) Serum lipides in acute pancreatitis. Gastroenterology 36:832

    PubMed  CAS  Google Scholar 

  14. Haig THB (1970) Experimental pancreatitis intensified by a high fat diet. Surg Gynecol Obstet 131:914

    Google Scholar 

  15. Cameron JL, Zuidema GD, Margolis S (1975) A pathogenesis for alcoholic pancreatitis. Surgery 77:754

    PubMed  CAS  Google Scholar 

  16. Cross DF (1969) Recurrent pancreatitis and fat-induced - hyperlipoproteinemia. JAMA 208:1494

    Article  PubMed  CAS  Google Scholar 

  17. Havel RJ (1969) Pathogenesis, differentiation and management of hypertriglyceridemia. Adv Intern Med 15:117

    PubMed  CAS  Google Scholar 

  18. Schneider J, Tesdorpf M, Kaffarnik H, Hausmann L, Zöfel P, Zilliken F (1976) Alteration of plasma lipids and intermediates of lipid metabolism in healthy fasting volunteers by ethanol and fructose. Res Exp Med 167:159

    Article  CAS  Google Scholar 

  19. Avogaro P, Cazzolato G (1975) Changes in the composition and physico-chemical characteristics of serum lipoproteins during ethanol-induced lipemia in alcoholic subjects. Metabolism 24:1231

    Article  PubMed  CAS  Google Scholar 

  20. Grande F, Hay LJ, Heupel HW, Amatuzio SS (1960) Effect of ethanol on serum cholesterol concentration in dog and man. Circ Res 8:810

    PubMed  CAS  Google Scholar 

  21. Verdy M, Gattereau A (1964) Ethanol, lipase activity and serum lipid level. Am J Clin Nutr 9:997

    Google Scholar 

  22. Eggstein M, Kreutz FH (1966) Eine neue Bestimmung der Neutralfette im Blutserum und Gewebe. Klin Wochenschr 44:262

    Article  PubMed  CAS  Google Scholar 

  23. Röschlau P, Bernt E, Gruber W (1974) Enzymatische Bestimmung des Gesamtcholesterins im Serum. Z Klin Chem Klin Biochem 12:403

    PubMed  Google Scholar 

  24. Rapp W, Kahlke W (1968) Lipoprotein-Elektrophorese in Agarosegel. Clin Chim Acta 19:493

    Article  PubMed  CAS  Google Scholar 

  25. Rakow AD, Klor HU, Leupold D, Ditschuneit HH, Ditschuneit H, Bremer HJ (1976) Therapieprobleme der Hyperlipoproteinämie Typ I. Klin Wochenschr 54:422–425

    Article  Google Scholar 

  26. Ditschuneit HH, Faulhaber JD, Hiller G, Klör HU, Mico L, Thun K, Ditschuneit H (1971) Die Darstellung von Lipoproteinen aus menschlichem Plasma mit Hilfe der Zonen-zentrifugation. Verh Dtsch Ges Inn Med 77:591

    PubMed  CAS  Google Scholar 

  27. Spiro HM (1970) Clinical gastroenterology. Collier Macmillan, London

    Google Scholar 

  28. Cameron JL (1985) Pancreatitis and hyperlipemia. In: Bockus (ed) Gastroenterology, 4th edn. Saunders, Philadelphia, pp 4055–4071

    Google Scholar 

  29. Klör HU (1978) Störungen des Lipid- und Lipoproteinstoffwechsels bei Le-bererkrankungen - Klinik und Pathogenese. Dissertation, University of Ulm

    Google Scholar 

  30. Bode G (1985) Atherogenese: Ein postprandiales Phänomen? Untersuchungen zum Stoff-wechsel triglyzeridreicher Lipoproteine unter besonderer Berücksichtigung elek-tronenmikroskopischer Methoden. Dissertation, University of Ulm

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Ditschuneit, H. (1987). Hyperlipoproteinemia in the Pathogenesis of Acute Pancreatitis. In: Beger, H.G., Büchler, M. (eds) Acute Pancreatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83027-3_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83027-3_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83029-7

  • Online ISBN: 978-3-642-83027-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics