Hemodynamic Effects of Unilateral Acute Lung Injury
For the purpose of this chapter, unilateral acute lung injury (ALI) must be considered as the result of a pathologic process that diffusely involves one lung, leaving the other unaffected. In some instances, the inflammatory reactions triggered by the etiologic agent cause the separation of the lungs into two units with totally different functional characteristics. In these cases, of particular concern for the therapist is the fact that conventional treatment often fails, or even leads to further deterioration of the clinical condition. Unilateral ALI refractory to conventional treatment therefore requires particular therapeutic maneuvres. It is evident that the knowledge of the pathophysiologic evolution of the disease is paramount for the treatment. In this context, the description of the derangements induced on the pulmonary and systemic hemodynamics needs particular emphasis, though the concomitant ventilatory disturbances should not be underestimated.
KeywordsRight Ventricular Acute Respiratory Failure Functional Residual Capacity Pulmonary Blood Flow Adult Respiratory Distress Syndrome
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