New Methods of Fibrin Sealant (Tissucol/Tisseel) Application in Maxillofacial Surgery: The Use of Hydroxyapatite in Association with Human Fibrin Glue in Reconstructive Surgery
Several ceramic compounds of calcium hydroxyapatite have been produced in the past 10 years and appear to offer hitherto unknown properties in terms of chemical composition and histocompatibility. The compounds, currently only marketed in a granular form, may be used in place of autologous bone grafts since they are biocompatible and also present no peripheral fibrous sulcus or conductivity. When mixed with fibrin cement the product has been found to have an even wider range of applications and has proved useful in oromaxillofacial surgery (to augment atrophied alveolar crests, in reconstructive surgery and in the surgical treatment of large cystic tumors). Histochemical and physical assessment of in vivo fragments confirm the properties of this new biological material.
Key wordsFibrin glue hydroxyapatite maxillofacial area
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