Glucagon — An Important Therapeutic Agent
Endocrinology is finding an increasing role and importance in Critical Care and Emergency Medicine. Hormones clearly mediate much of the body’s homeostatic response to critical illness . For example, catecholamines, aldosterone and anti-diuretic hormone are each released into the circulation during states of hypotension and shock. Endocrine and metabolic problems are common in critically ill patients. More than two-thirds of critically ill patients manifest abnormalities (at least biochemically) in either thyroid function , calcium metabolism [2, 21], or magnesium metabolism . Hormones are also important therapeutic agents. Many hormones, peptides and receptor antagonists have been considered in the treatment of shock . The purpose of this paper is to review the pharmacology and physiology of the hormone glucagon — as it applies to critical and emergency care.
KeywordsMagnesium Hepatitis Cortisol Hull Peris
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